Evidence map›Paper›PMID 27630961›Full record

ArticleJournal of clinical and diagnostic research : JCDR2016

A Comparative Analysis of Cytokeratin 18 and 19 Expressions in Odontogenic Keratocyst, Dentigerous Cyst and Radicular Cyst with a Review of Literature.

Vikas Parshottam Bhakhar, Vandana Sandip Shah, Mohsin Jiva Ghanchi, Sandesh Sachchidanand Gosavi, Himanshu Mahesh Srivastava, Nivedita Javahir Pachore

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. The correlated expression of COX-2 and keratin 15 in radicular cysts.Journal of clinical and experimental dentistry · 2022
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Vikas Parshottam BhakharSenior Lecturer, Department of Oral Pathology, College of Dental Science , Bhavnagar, Gujarat, India .
Vandana Sandip ShahProfessor and Head, Department of Oral Pathology, K. M. Shah Dental College , Vadodara, Gujarat, India .
Mohsin Jiva GhanchiProfessor and Head, Department of Oral Pathology, College of Dental Science , Bhavnagar, Gujarat, India .
Sandesh Sachchidanand GosaviDean, College of Dental Science , Bhavnagar, Gujarat, India .
Himanshu Mahesh SrivastavaPost Graduate Student, Department of Oral Pathology, K. M. Shah Dental College , Vadodara, Gujarat, India .
Nivedita Javahir PachoreSenior Lecturer, Department of Prosthodontics, College of Dental Science , Bhavnagar, Gujarat, India .
Bhavnagar University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOdontogenic cysts viz Odontogenic Keratocyst (OKC), Dentigerous Cyst (DC) and Radicular Cyst (RC) occur commonly in the oral and maxillofacial region. Cytokeratin (CK) expression studies have been done to evaluate diagnostic accuracy, role in pathogenesis, elucidate behaviour and role in treatment protocols. However, variations have been reported in the expression of CK patterns in these odontogenic cysts, which could be due to the lack of standardization of laboratory techniques. The present study has tried to shed light on CK 18 and 19 expression in odontogenic cysts and offer the brief review of previous studies on these CK.

aimThe aim of the present study was to evaluate the intensity and expression patterns of CK 18 and 19 in OKCs, DCs and RCs. MATERIALS AND

methodsA total of 60 cases, 20 each of OKC, DC and RC were confirmed histologically and evaluated for immunohistochemical expression pattern and intensity of CK 18 and 19.

resultsA focal and variable expression of CK 18 was observed in 25% of OKCs, 15% of DCs and 10% of RCs. CK 19 was expressed in 75% of OKCs and 100% in DCs as well as RCs.

conclusionThe intensity and expression of Cytokeratin 19 was more in all three cysts compared to Cytokeratin 18.

Indexed as

ComparisonDiagnosisIntensity

Identifiers

PMID27630961
PMCPMC5020168
OpenAlexW2537796980

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.