ArticleJournal of clinical and diagnostic research : JCDR2016
Role of Histomorphology and Chronic Inflammation Score in Chronic Dacryocystitis.
Article in Journal of clinical and diagnostic research : JCDR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Evaluation of inflammation-related histopathological changes in the lacrimal sac, nasal bone, and nasal mucosa in cases of primary acquired nasolacrimal duct obstruction.International ophthalmology · 2026Article
- Research on animal models of chronic dacryocystitis in dogs.BMC ophthalmology · 2026Article
- Computed tomographic dacryocystography combined with multiplanar reconstruction technique in lacrimal duct probe placement.BMC ophthalmology · 2026Article
- Evaluation of the clinical efficacy of endoscopic endonasal dacryocystorhinostomy in treating chronic dacryocystitis.Frontiers in medicine · 2026Article
- Vision-Related Quality of Life Outcomes Following Endoscopic Dacryocystorhinostomy in Chronic Dacryocystitis: A Prospective Cohort Study.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Results and clinical aspects of primary endonasal endoscopic dacryocystorhinostomy with silicone tube.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022Article
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4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionDiseases of lacrimal drainage system account for nearly 3% of visits to eye clinic. Chronic dacryocystitis is a frequently encountered disorder among these patients. Histomorphology of specimens obtained after Dacryocystorhinostomy (DCR) is a pertinent indicator of prognostic outcome.
aimThe aim of the study was to evaluate histopathology of specimens obtained after DCR and to elucidate patterns and score of chronic inflammation encountered. MATERIALS AND
methodsThe study was conducted for a period of one year. Total of 50 patients who were clinically diagnosed as Chronic Dacryocystitis and underwent DCR were included. Following DCR, specimens of lacrimal sac, nasal mucous membrane and nasal bone were collected. Histopathological slides were examined for chronic inflammatory cell infiltration, fibrosis and capillary proliferation and were graded according to severity, in each specimen. A Chronic Inflammation Score (CIS) was recorded for each case.
resultsThe average age of patients was 39.04±14.22 years and their age ranged between 13 and 62 years. There were 28 (56%) females and 22 (44%) males in the study group. The nasal bone did not reveal any abnormality in any case. The nasal mucous membrane showed mild chronic inflammatory cell infiltration in 46 (92%) cases and moderate degree in 4 (8%) patients. Chronic inflammation with granulation tissue formation was noted in lacrimal sacs of all patients. The CIS revealed that 14 (28%) cases belonged to "mild" group, 26 (52%) to "moderate" group and 10 (20%) to "severe" category.
conclusionThe inclusion of CIS in histomorphological evaluation of DCR specimens is recommended since it is one of the parameters that influence course of the disease.
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