Evidence map›Paper›PMID 27630807›Full record

ArticleChemPlusChem2016

Macrocycle-Based Hydroxamate Ligands for Complexation and Immunoconjugation of

Eszter Boros, Jason P Holland, Nathaniel Kenton, Nicholas Rotile, Peter Caravan

Open access · greenAbstract read
In one paragraph

Article in ChemPlusChem, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. A Semi Rigid Novel Hydroxamate AMPED-Based Ligand forMolecules (Basel, Switzerland) · 2021
    Article
  6. Article
  7. Review
  8. Review
  9. Head-to-head comparison of DFO* and DFO chelators: selection of the best candidate for clinicalEuropean journal of nuclear medicine and molecular imaging · 2021
    Article
  10. Polyazamacrocycle Ligands FacilitateInorganic chemistry · 2020
    Article
  11. Article
  12. Article
  13. Review
  14. Direct comparison of the in vitro and in vivo stability of DFO, DFO* and DFOcyclo* forEuropean journal of nuclear medicine and molecular imaging · 2019
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Recent Advances in Zirconium-89 Chelator Development.Molecules (Basel, Switzerland) · 2018
    Review
  20. Bioconjugate chemistry · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Eszter BorosThe Athinoula A. Martinos Center for Biomedical Imaging Department of Radiology, Massachusetts General Hospital Harvard Medical School, 149 Thirteenth Street, Suite 2301 Charlestown, MA 02129 (USA).
Jason P HollandDivision of Nuclear Medicine and Molecular Imaging Massachusetts General Hospital, Department of Radiology Harvard Medical School, 55 Fruit Street, White 427 Boston, MA 02114 (USA).
Nathaniel KentonThe Athinoula A. Martinos Center for Biomedical Imaging Department of Radiology, Massachusetts General Hospital Harvard Medical School, 149 Thirteenth Street, Suite 2301 Charlestown, MA 02129 (USA).
Nicholas RotileThe Athinoula A. Martinos Center for Biomedical Imaging Department of Radiology, Massachusetts General Hospital Harvard Medical School, 149 Thirteenth Street, Suite 2301 Charlestown, MA 02129 (USA).
Peter CaravanThe Athinoula A. Martinos Center for Biomedical Imaging Department of Radiology, Massachusetts General Hospital Harvard Medical School, 149 Thirteenth Street, Suite 2301 Charlestown, MA 02129 (USA).
Harvard University · USMassachusetts General Hospital · USAthinoula A. Martinos Center for Biomedical Imaging · US

Funding

Stable, High Relaxivity MRI Contrast AgentsR01EB009062 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI CARAVAN, PETER D · 2009 to 2017
$4.9M
Inveon: A Triple Modality Biomedical Imaging SystemS10RR029495 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI BROWNELL, ANNA-LIISA · 2010 to 2010
$1.3M
Development of Zr-89 based immunoPET agents for idiopathic pulmonary fibrosisR00HL125728 · NHLBI · STATE UNIVERSITY NEW YORK STONY BROOK · PI BOROS, ESZTER · 2018 to 2020
$744k
500 MHz NMR Spectrometer for Molecular Imaging ApplicationsS10RR023385 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 2007 to 2007
$500k
Upgrade for Biospec Console and accessories for the 9.4T/20cm MagnetS10RR025563 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI DAI, GUANGPING · 2009 to 2009
$498k
HPLC-ICP-MS SystemS10OD010650 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI CARAVAN, PETER D · 2013 to 2013
$371k
IVIS Spectrum Imaging SystemS10RR025504 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI MOORE, ANNA · 2009 to 2009
$341k
Development of Zr-89 based ImmunoPET agents for Idiopathic Pulmonary FibrosisK99HL125728 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI BOROS, ESZTER · 2015 to 2016
$311k
NCRR NIH HHS S10 RR023385NCRR NIH HHS S10 RR025563NCRR NIH HHS S10 RR029495NHLBI NIH HHS K99 HL125728NHLBI NIH HHS R00 HL125728NIBIB NIH HHS R01 EB009062NIH HHS S10 OD010650
6 · The paper itself

Abstract

Four novel chelators (

Indexed as

antitumor agentsimaging agentsmacrocyclesradiopharmaceuticalszirconium

Identifiers

PMID27630807
PMCPMC5019580
OpenAlexW2261465365

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.