Evidence map›Paper›PMID 27630231›Full record

ArticleJournal of virology2016

Dynamics and Correlates of CD8 T-Cell Counts in Africans with Primary Human Immunodeficiency Virus Type 1 Infection.

Heather A Prentice, Hailin Lu, Matthew A Price, Anatoli Kamali, Etienne Karita, Shabir Lakhi, Eduard J Sanders, Omu Anzala, Susan Allen, Paul A Goepfert and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Heather A PrenticeDepartment of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Hailin LuDepartment of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Matthew A PriceInternational AIDS Vaccine Initiative, New York, New York, USA.
Anatoli KamaliMRC/UVRI Uganda Virus Research Unit on AIDS, Masaka Site, Masaka, Uganda.
Etienne KaritaProject San Francisco, Kigali, Rwanda.
Shabir LakhiZambia-Emory HIV Research Project, Lusaka, Zambia.
Eduard J SandersCentre for Geographic Medicine Research, Kenya Medical Research Institute, Kilifi, Kenya.
Omu AnzalaKenya AIDS Vaccine Initiative, Nairobi, Kenya.
Susan AllenProject San Francisco, Kigali, Rwanda.
Paul A GoepfertDepartment of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Eric HunterVaccine Research Center, Emory University, Atlanta, Georgia, USA.
Jill GilmourInternational AIDS Vaccine Initiative, Human Immunology Laboratory, Chelsea and Westminster Hospital, London, United Kingdom.
Jianming TangDepartment of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA jtang@uab.edu.

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
CTL and HIV Polymorphisms in Heterosexual TransmissionR01AI064060 · NIAID · EMORY UNIVERSITY · PI GOEPFERT, PAUL A., HUNTER, ERIC · 2005 to 2019
$21.7M
EMORY AIDS INTERNATIONAL TRAINING AND RESEARCH PROGRAMD43TW001042 · FIC · EMORY UNIVERSITY · PI DEL RIO, CARLOS · 1998 to 2013
$6.8M
FIC NIH HHS D43 TW001042NIAID NIH HHS R01 AI064060NIH HHS P51 OD011132Wellcome Trust
6 · The paper itself

Abstract

In individuals with HIV-1 infection, depletion of CD4 IMPORTANCE: Longitudinal data from 497 HIV-1 seroconverters allowed us to systematically evaluate the dynamics and correlates of CD8

Indexed as

AdultAfricaBlack PeopleCD4 Lymphocyte CountCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesFemaleGenotypeHIV-1HIV InfectionsHIV SeropositivityHumansMaleViral Load

Identifiers

PMID27630231
PMCPMC5105675

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.