Evidence map›Paper›PMID 27630137›Full record

ArticleCirculation2016

Could Modification of Titin Contribute to an Answer for Heart Failure With Preserved Ejection Fraction?

Martin M LeWinter, Michael R Zile

Abstract readEditorialComment
In one paragraph

Article in Circulation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Role of mineralocorticoid receptor activation in cardiac diastolic dysfunction.Biochimica et biophysica acta. Molecular basis of disease · 2017
    Review
  8. Autoantibody profiling on a plasmonic nano-gold chip for the early detection of hypertensive heart disease.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Martin M LeWinterFrom Cardiology Unit, University of Vermont College of Medicine, Burlington (M.M.L.); and RHJ Department of Veterans Affairs Medical Center and the Medical University of South Carolina, Charleston (M.R.Z.). martin.lewinter@uvmhealth.org.
Michael R ZileFrom Cardiology Unit, University of Vermont College of Medicine, Burlington (M.M.L.); and RHJ Department of Veterans Affairs Medical Center and the Medical University of South Carolina, Charleston (M.R.Z.).

Funding

Advanced Glycation End-Products in Human MyocardiumR01HL089944 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI LEWINTER, MARTIN M · 2008 to 2011
$2.6M
Myofilament-based mechanisms of diastolic dysfunction in HFpEFR01HL118524 · NHLBI · UNIVERSITY OF ARIZONA · PI GRANZIER, HENK L., LEWINTER, MARTIN M · 2014 to 2017
$2.5M
New England, New York and Quebec Regional Clinical CenterU10HL110342 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI HUGGINS, GORDON S, VANBUREN, PETER C · 2012 to 2018
$2.3M
Extracellular Matrix in Hypertensive Heart Disease & Transition to Heart FailureR01HL123478 · NHLBI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI ZILE, MICHAEL R · 2015 to 2018
$1.5M
Extracellular Matrix in Hypertensive Heart Disease & Transition to Heart FailureR56HL123478 · NHLBI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI ZILE, MICHAEL R · 2014 to 2014
$387k
NHLBI NIH HHS R01 HL089944NHLBI NIH HHS R01 HL118524NHLBI NIH HHS R01 HL123478NHLBI NIH HHS R56 HL123478NHLBI NIH HHS U10 HL110342
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ConnectinStroke VolumeHeart FailureHumansMyocardiumConnectinEditorialsheart diseasesheart failure

Identifiers

PMID27630137
PMCPMC5069174

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.