ArticleJournal of clinical laboratory analysis2017
A novel turbidimetric immunoassay for fecal calprotectin optimized for routine chemistry analyzers.
Article in Journal of clinical laboratory analysis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Diagnostic value of leucine-rich alpha-2-glycoprotein 1 and calprotectin in acute appendicitis: a short review.Biochemia medica · 2025Review
- Performance Evaluation of Open Channel Buhlmann Fecal Calprotectin Turbo Assay on Abbott Alinity C Analyzer.Diagnostics (Basel, Switzerland) · 2024Article
- Validation of rapid fecal calprotectin assay using particle enhanced turbidimetric immunoassay for inflammatory bowel disease.Scientific reports · 2024Article
- Verification of the Bühlmann fCAL turbo faecal calprotectin assay on the Binding Site Optilite benchtop analyser.Practical laboratory medicine · 2023Article
- Chicken antibodies are highly suitable for particle enhanced turbidimetric assays.Frontiers in immunology · 2022Article
- Experimental infectious challenge in pigs leads to elevated fecal calprotectin levels following colitis, but not enteritis.Porcine health management · 2021Article
- International consensus on methodological issues in standardization of fecal calprotectin measurement in inflammatory bowel diseases.United European gastroenterology journal · 2021Article
- Validation of the newly FDA-approved Buhlmann fCal Turbo assay for measurement of fecal calprotectin in a pediatric population.Practical laboratory medicine · 2020Article
- Analytical and clinical performance of the fully-automated LIAISONXL calprotectin immunoassay from DiaSorin in IBD patients.Practical laboratory medicine · 2020Article
- Evaluation of a fluorescent immunochromatography test for fecal calprotectin.Journal of clinical laboratory analysis · 2020Article
- The Vampire Study: Significant elevation of faecal calprotectin in healthy volunteers after 300 ml blood ingestion mimicking upper gastrointestinal bleeding.United European gastroenterology journal · 2018Article
- Analytical evaluation of a fully automated immunoassay for faecal calprotectin in a paediatric setting.Biochemia medica · 2017Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFecal calprotectin assays are widely used to exclude inflammatory bowel disease (IBD) in patients with suspected IBD. A problem with the fecal calprotectin assays is the rather long test-turnaround times. A particle enhanced turbidimetric immunoassays (PETIA) for fecal calprotectin would reduce test-turnaround times and would permit more laboratories to perform the measurements. The aim of this study was to evaluate a new feces calprotectin PETIA.
methodUsing routine fecal samples the feces calprotectin PETIA was validated on two chemistry analyzers, Mindray BS-380 and Cobas 501.
resultsThe assay is linear in the range 11-2000 μg/g, with a limit of quantitation of approximately 10 μg/g. No antigen excess hook effect was observed up to 10 000-15 000 μg/g depending on the instrument used. The turbidimetric method showed a good agreement with the Bühlmann ELISA. The total coefficient of variation was 3%-8% in the 50-100 μg/g range.
conclusionThe fecal calprotectin PETIA, fCal Turbo, is well suited for rapid analysis of fecal calprotectin on Mindray BS-380 or Cobas 501 clinical chemistry analyzers. The test results are commutable with Bühlmann fecal MRP8/14 ELISA.
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