Evidence map›Paper›PMID 27629578›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2016

Long-term treatment of spontaneously hypertensive rats with PD123319 and electrophysiological remodeling of left ventricular myocardium.

Xiao Ying, Guan Kai-Pan, Long Wei-Qing, Peng Long-Yun, Wu De-Xi, Huang Zhi-Bin

Abstract read
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In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xiao YingDepartment of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, China.
Guan Kai-PanDepartment of Respiratory Intensive Care Unit, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, China.
Long Wei-QingDepartment of Clinical Laboratory, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, China.
Peng Long-YunDepartment of Cardiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, China.
Wu De-XiDepartment of Cardiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, China.
Huang Zhi-BinDepartment of Cardiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, China. hzbin2603@163.com.
Sun Yat-sen University · CNThe First Affiliated Hospital, Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate the effects of PD123319, an antagonist of angiotensin II subtype-2 receptor (AT2R), on the electrophysiological characteristics of the left ventricular hypertrophic myocardium in spontaneously hypertensive rats (SHR). A total of twenty-four 10-week-old male SHR were divided into two groups: PD123319 and non-PD123319 groups (n = 12 in each). Twelve 10-week-old Wistar-Kyoto rats served as the control group. Systolic blood pressure, left ventricular mass index (LVMI), ventricular effective refractory period, and ventricular fibrillation threshold were also measured after 8 weeks. I

Indexed as

Action PotentialsAngiotensin II Type 2 Receptor BlockersAnimalsAntihypertensive AgentsBlood PressureDisease Models, AnimalElectric CapacitanceHeart VentriclesHypertensionHypertrophy, Left VentricularImidazolesMalePyridinesRats, Inbred SHRRats, Inbred WKYRefractory Period, ElectrophysiologicalAngiotensin II Type 2 Receptor BlockersAntihypertensive AgentsImidazolesPD 123319PyridinesElectrophysiologyHypertensionHypertrophyPD123319

Identifiers

PMID27629578
OpenAlexW2520130839

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.