ArticleClinical rheumatology2016
IL-9-producing Th9 cells may participate in pathogenesis of Takayasu's arteritis.
Article in Clinical rheumatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- Targeting Th9 cells in autoimmune diseases: a narrative review.Frontiers in immunology · 2025Review
- The role of CD8Clinical rheumatology · 2022Article
- Advances in Takayasu arteritis: An Asia Pacific perspective.Frontiers in medicine · 2022Review
- Using the co-expression network of T cell-activation-related genes to assess the disease activity in Takayasu's arteritis patients.Arthritis research & therapy · 2021Article
- Application progress of multiple imaging modalities in Takayasu arteritis.The international journal of cardiovascular imaging · 2021Review
- Identification of the Association Between Toll-Like Receptors and T-Cell Activation in Takayasu's Arteritis.Frontiers in immunology · 2021Article
- Pathogenesis of liver injury in Takayasu arteritis: advanced understanding leads to new horizons.The Journal of international medical research · 2020Article
- Interleukin-9 blockage reduces early hepatic granuloma formation and fibrosis during Schistosoma japonicum infection in mice.Immunology · 2019Article
- Takayasu arteritis with pyoderma gangrenosum: case reports and literature review.BMC rheumatology · 2019Article
- New Insights on the Pathogenesis of Takayasu Arteritis: Revisiting the Microbial Theory.Pathogens (Basel, Switzerland) · 2018Review
- A case of primarily facial pyoderma gangrenosum associated with Takayasu arteritis.JAAD case reports · 2017Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Takayasu's arteritis (TAK) is a type of large vessel vasculitis which involves the aorta and its major branches. Interleukin (IL)-9 or IL-9-producing Th9 cells were found to be involved in pathogenesis of autoimmune arteritis such as giant cell arteritis, but IL-9 or Th9 cells in TAK were not well known. Here, this study aims to analyze the levels of serum IL-9 and their major source Th9 cells in TAK. With the help of cytometric bead array (CBA), a total of 21 patients with TAK were examined for serum levels of cytokines IL-4, IL-6, IL-8, IL-17, IL-10, TNF-α, IFN-γ, and IL-9. Flow cytometry techniques were used to examine the frequencies of Th9 cells from peripheral blood mononuclear cells (PBMCs) for 11 patients with active TAK and 10 healthy controls. Higher serum levels of serum IL-6 (P < 0.05), TNF-α (P < 0.05), and IL-9 level (P < 0.05) were observed in TAK patients compared to those of healthy controls. Higher frequencies of CD4
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