ArticleFrontiers in immunology2016
Commentary: A Metabolic Immune Checkpoint: Adenosine in Tumor Microenvironment.
Article in Frontiers in immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- CD73: a new immune checkpoint for leukemia treatment.Frontiers in immunology · 2025Review
- How lactate affects immune strategies in lymphoma.Frontiers in molecular biosciences · 2024Review
- Glycoengineered anti-CD39 promotes anticancer responses by depleting suppressive cells and inhibiting angiogenesis in tumor models.The Journal of clinical investigation · 2022Article
- Tumor-Derived Lactate Creates a Favorable Niche for TumorFrontiers in cell and developmental biology · 2022Review
- CD73 blockade enhances the local and abscopal effects of radiotherapy in a murine rectal cancer model.BMC cancer · 2020Article
- Contribution of ROS and metabolic status to neonatal and adult CD8+ T cell activation.PloS one · 2019Article
- The Adaptive Complexity of Cancer.BioMed research international · 2018Review
- Accomplices of the Hypoxic Tumor Microenvironment Compromising Antitumor Immunity: Adenosine, Lactate, Acidosis, Vascular Endothelial Growth Factor, Potassium Ions, and Phosphatidylserine.Frontiers in immunology · 2017Review
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.