Evidence map›Paper›PMID 27629098›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2017

Comparison of two PET radioligands, [

Talakad G Lohith, Tetsuya Tsujikawa, Fabrice G Siméon, Mattia Veronese, Sami S Zoghbi, Chul Hyoung Lyoo, Yasuyuki Kimura, Cheryl L Morse, Victor W Pike, Masahiro Fujita and 1 more

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Test-retest properties of [EJNMMI research · 2025
    Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. [EJNMMI radiopharmacy and chemistry · 2019
    Review
  10. Characterization of [Molecular imaging and biology · 2019
    Article
  11. Radiolabeling with [Nuclear medicine and biology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Talakad G Lohith1 Molecular Imaging Branch, National Institute of Mental Health, Bethesda, USA.
Tetsuya Tsujikawa1 Molecular Imaging Branch, National Institute of Mental Health, Bethesda, USA.
Fabrice G Siméon1 Molecular Imaging Branch, National Institute of Mental Health, Bethesda, USA.
Mattia Veronese1 Molecular Imaging Branch, National Institute of Mental Health, Bethesda, USA.
Sami S Zoghbi1 Molecular Imaging Branch, National Institute of Mental Health, Bethesda, USA.
Chul Hyoung Lyoo1 Molecular Imaging Branch, National Institute of Mental Health, Bethesda, USA.
Yasuyuki Kimura1 Molecular Imaging Branch, National Institute of Mental Health, Bethesda, USA.
Cheryl L Morse1 Molecular Imaging Branch, National Institute of Mental Health, Bethesda, USA.
Victor W Pike1 Molecular Imaging Branch, National Institute of Mental Health, Bethesda, USA.
Masahiro Fujita1 Molecular Imaging Branch, National Institute of Mental Health, Bethesda, USA.
Robert B Innis1 Molecular Imaging Branch, National Institute of Mental Health, Bethesda, USA.
National Institute of Mental Health · USKing's College London · GB

Funding

PET Radiopharmaceutical SciencesZIAMH002793 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PIKE, VICTOR W · 2009 to 2025
$69.8M
Medical Research Council G1100809Medical Research Council MC_U120085814
6 · The paper itself

Abstract

Of the two

Indexed as

AdultBrainCarbon RadioisotopesFemaleHealthy VolunteersHumansImage Processing, Computer-AssistedLigandsMaleModels, BiologicalNitrilesPositron-Emission TomographyPyridinesRadionuclide ImagingRadiopharmaceuticalsReceptor, Metabotropic Glutamate 53-fluoro-5-(2-(2-(fluoromethyl)thiazol-4-yl)ethynyl)benzonitrile3-fluoro-5-((pyridin-3-yl)ethynyl)benzonitrileCarbon RadioisotopesGRM5 protein, humanLigandsNitrilesPyridinesRadiopharmaceuticalsReceptor, Metabotropic Glutamate 5RNA, MessengerThiazolesFPEBgenomic plotmGluR5PET imagingSP203

Identifiers

PMID27629098
PMCPMC5531344
OpenAlexW2520847438

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.