ArticleJournal of neurophysiology2016
Slow gamma rhythms in CA3 are entrained by slow gamma activity in the dentate gyrus.
Article in Journal of neurophysiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 35 citations in OpenAlex.
- Gamma suppression correlates with thalamic stimulation therapeutic response in intractable epilepsy.Epilepsia · 2026Article
- Dynamics of Dentate Gyrus Place Cells and Dentate Spikes during Spatial and Nonspatial Changes in Environments.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Spectral dependence as a framework for neural coordination.Current research in neurobiology · 2026Article
- Article
- Hippocampal Place Cell Sequences Are Impaired in a Rat Model of Fragile X Syndrome.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Social odors drive hippocampal CA2 place cell responses to social stimuli.Progress in neurobiology · 2025Article
- Effects of Sarcosine (N-methylglycine) on NMDA (N-methyl-D-aspartate) Receptor Hypofunction Induced by MK801: In Vivo Calcium Imaging in the CA1 Region of the Dorsal Hippocampus.Brain sciences · 2024Article
- Social odors drive hippocampal CA2 place cell responses to social stimuli.bioRxiv : the preprint server for biology · 2024Article
- The medial septum controls hippocampal supra-theta oscillations.Nature communications · 2023Article
- Article
- Review
- Theta dominates cross-frequency coupling in hippocampal-medial entorhinal circuit during awake-behavior in rats.iScience · 2022Article
- Running speed and REM sleep control two distinct modes of rapid interhemispheric communication.Cell reports · 2022Article
- Population and individual firing behaviors in sparsely synchronized rhythms in the hippocampal dentate gyrus.Cognitive neurodynamics · 2022Article
- Quantitative properties of a feedback circuit predict frequency-dependent pattern separation.eLife · 2020Article
- Five Decades of Hippocampal Place Cells and EEG Rhythms in Behaving Rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Review
- CA3 place cells that represent a novel waking experience are preferentially reactivated during sharp wave-ripples in subsequent sleep.Hippocampus · 2019Article
- Comparison of three gamma oscillations in the mouse entorhinal-hippocampal system.The European journal of neuroscience · 2018Article
- Dentate network activity is necessary for spatial working memory by supporting CA3 sharp-wave ripple generation and prospective firing of CA3 neurons.Nature neuroscience · 2018Article
- Time and frequency dependent changes in resting state EEG functional connectivity following lipopolysaccharide challenge in rats.PloS one · 2018Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
In hippocampal area CA1, slow (∼25-55 Hz) and fast (∼60-100 Hz) gamma rhythms are coupled with different CA1 afferents. CA1 slow gamma is coupled to inputs from CA3, and CA1 fast gamma is coupled to inputs from the medial entorhinal cortex (Colgin LL, Denninger T, Fyhn M, Hafting T, Bonnevie T, Jensen O, Moser MB, Moser EI. Nature 462: 353-357, 2009). CA3 gives rise to highly divergent associational projections, and it is possible that reverberating activity in these connections generates slow gamma rhythms in the hippocampus. However, hippocampal gamma is maximal upstream of CA3, in the dentate gyrus (DG) region (Bragin A, Jando G, Nadasdy Z, Hetke J, Wise K, Buzsaki G. J Neurosci 15: 47-60, 1995). Thus it is possible that slow gamma in CA3 is driven by inputs from DG, yet few studies have examined slow and fast gamma rhythms in DG recordings. Here we investigated slow and fast gamma rhythms in paired recordings from DG and CA3 in freely moving rats to determine whether slow and fast gamma rhythms in CA3 are entrained by DG. We found that slow gamma rhythms, as opposed to fast gamma rhythms, were particularly prominent in DG. We investigated directional causal influences between DG and CA3 by Granger causality analysis and found that DG slow gamma influences CA3 slow gamma. Moreover, DG place cell spikes were strongly phase-locked to CA3 slow gamma rhythms, suggesting that DG excitatory projections to CA3 may underlie this directional influence. These results indicate that slow gamma rhythms do not originate in CA3 but rather slow gamma activity upstream in DG entrains slow gamma rhythms in CA3.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.