Evidence map›Paper›PMID 27628203›Full record

ArticleJournal of neurophysiology2016

Activation of β-noradrenergic receptors enhances rhythmic bursting in mouse olfactory bulb external tufted cells.

Fu-Wen Zhou, Hong-Wei Dong, Matthew Ennis

Open access · bronzeAbstract read
In one paragraph

Article in Journal of neurophysiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  11. Stimulation of the Locus Ceruleus Modulates Signal-to-Noise Ratio in the Olfactory Bulb.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Fu-Wen ZhouDepartment of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, Tennessee fzhou4@uthsc.edu.ORCID 0000-0002-3500-666X
Hong-Wei DongDepartment of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, Tennessee.
Matthew EnnisDepartment of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, Tennessee.
University of Tennessee Health Science Center · US

Funding

CRCNS: Computational and experimental analysis of noradrenergic function in earlyR01DC008702 · NIDCD · CORNELL UNIVERSITY · PI LINSTER, CHRISTIANE · 2006 to 2010
$1.6M
NIDCD NIH HHS R01 DC008702
6 · The paper itself

Abstract

The main olfactory bulb (MOB) receives a rich noradrenergic innervation from the nucleus locus coeruleus. Despite the well-documented role of norepinephrine and β-adrenergic receptors in neonatal odor preference learning, identified cellular physiological actions of β-receptors in the MOB have remained elusive. β-Receptors are expressed at relatively high levels in the MOB glomeruli, the location of external tufted (ET) cells that exert an excitatory drive on mitral and other cell types. The present study investigated the effects of β-receptor activation on the excitability of ET cells with patch-clamp electrophysiology in mature mouse MOB slices. Isoproterenol and selective β

Indexed as

PeriodicityAdrenergic AgentsAnalysis of VarianceAnimalsBiophysical PhenomenaCardiotonic AgentsElectric StimulationFemaleIn Vitro TechniquesMaleMembrane PotentialsMiceNeuronsNeurotransmitter AgentsNorepinephrineOlfactory BulbAdrenergic AgentsCardiotonic AgentsICI D2788Neurotransmitter AgentsNorepinephrinePyrimidinesReceptors, Adrenergic, betaburstingexternal tufted cellshyperpolarization-activated cation currentisoproterenolpersistent sodium current

Identifiers

PMID27628203
PMCPMC5133314
OpenAlexW2519983167

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.