Evidence map›Paper›PMID 27628045›Full record

Trial reportJournal of bone and mineral metabolism2017

Maternal vitamin D supplementation in pregnancy and offspring outcomes: a double-blind randomized placebo-controlled trial.

Saroj Kumar Sahoo, Kishore Kumar Katam, Vinita Das, Anjoo Agarwal, Vijayalakshmi Bhatia

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of bone and mineral metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 13 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 13 syntheses or guidelines pooled it, 49 citations in OpenAlex.

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  5. Vitamin D supplementation for women during pregnancy.The Cochrane database of systematic reviews · 2024
    Pooled it
  6. The effect of pregnancy vitamin D supplementation on offspring bone mineral density in childhood: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023
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  10. Vitamin D supplementation for women during pregnancy.The Cochrane database of systematic reviews · 2019
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  14. Trial
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  16. Early Life Programming of Skeletal Health.Current osteoporosis reports · 2023
    Review
  17. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Saroj Kumar SahooSanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
Kishore Kumar KatamSanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
Vinita DasKing George's Medical University, Lucknow, India.
Anjoo AgarwalKing George's Medical University, Lucknow, India.
Vijayalakshmi BhatiaSanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India. bhatiaviji@gmail.com.
Sanjay Gandhi Post Graduate Institute of Medical Sciences · INKing George's Medical University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied bone mineral content (BMC), bone mineral density (BMD), and body composition in offspring of women supplemented with vitamin D during pregnancy. Pregnant women were randomized to receive oral cholecalciferol 60,000 units 4 weekly (group 1), 8 weekly (group 2), or placebo (group 3). All received 1 g calcium daily (groups 1 and 2 without, and group 3 with 400 units vitamin D). Offspring at 12-16 months underwent dual-energy X-ray absorptiometry. Maternal hypovitaminosis D at recruitment was common (serum 25OHD <50 nmol/L in 88 %) and severe (25OHD <25 nmol/L in 46 %). Groups 1 and 2 (n = 23 and 13, median age 14 months) had higher cord blood 25OHD (47.8 ± 13.8 and 31.0 ± 14.0 nmol/L) versus group 3 (n = 16, median age 16 months, 17.8 ± 13.5 nmol/L, p < 0.001). Babies in group 3 had higher whole-body BMC (250.8 ± 42.5 gm) and BMD (0.335 ± 0.033 gm/cm

Indexed as

Dietary SupplementsAbsorptiometry, PhotonAdultBody CompositionBone and BonesBone DensityCholecalciferolDouble-Blind MethodFemaleHumansInfantPlacebosPregnancyRegression AnalysisVitamin DCholecalciferolPlacebosVitamin DBody compositionBone healthInfectionsMaternal vitamin D supplementationOffspring

Identifiers

PMID27628045
OpenAlexW2519839036

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.