Evidence map›Paper›PMID 27627986›Full record

Observational studyIntegrative cancer therapies2017

Interest in Integrative Medicine Among Postmenopausal Hormone Receptor-Positive Breast Cancer Patients in the EvAluate-TM Study.

Carolin C Hack, Peter A Fasching, Tanja Fehm, Johann de Waal, Mahdi Rezai, Bernd Baier, Gerold Baake, Hans-Christian Kolberg, Martin Guggenberger, Mathias Warm and 40 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Integrative cancer therapies, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

50 authors.

Carolin C Hack1 Universitäts-Brustzentrum Franken, Frauenklinik, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-European Metropolitan area Nuremberg (CCC ER-EMN), Germany.
Peter A Fasching1 Universitäts-Brustzentrum Franken, Frauenklinik, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-European Metropolitan area Nuremberg (CCC ER-EMN), Germany.
Tanja Fehm2 Universitäts-Frauenklinik Düsseldorf, Düsseldorf, Germany.
Johann de Waal4 Frauenklinik im Klinikum Dachau, Dachau, Germany.
Mahdi Rezai5 Luisenkrankenhaus Düsseldorf, Düsseldorf, Germany.
Bernd Baier4 Frauenklinik im Klinikum Dachau, Dachau, Germany.
Gerold Baake6 Onkologische Praxis Pinneberg, Pinneberg, Germany.
Hans-Christian Kolberg7 Marienhospital Bottrop, Bottrop, Germany.
Martin Guggenberger8 Klinikum Tuttlingen, Germany.
Mathias Warm9 Brustzentrum, Universitäts-Frauenklinik, Cologne, Germany.
Nadia Harbeck3 Department für Frauengesundheit, Universitätsklinikum Tübingen, Eberhard-Karls-Universität, Tübingen, Germany.
Rachel Wuerstlein3 Department für Frauengesundheit, Universitätsklinikum Tübingen, Eberhard-Karls-Universität, Tübingen, Germany.
Jörg-Uwe Deuker12 Vinzenzkrankenhaus Hanover gGmbH, Hanover, Germany.
Peter Dall13 Frauenklinik, Städtisches Klinikum Lüneburg, Lüneburg, Germany.
Barbara Richter14 Elblandkliniken Meissen-Radebeul, Radebeul, Germany.
Grischa Wachsmann15 Kreiskrankenhaus Böblingen, Böblingen, Germany.
Cosima Brucker16 Universitätsklinik für Frauenheilkunde, Paracelsus Medizinische Privatuniversität, Nuremberg, Germany.
Jan W Siebers17 Frauenklinik der St. Josefsklinik, Offenburg, Germany.
Nikos Fersis18 Frauenklinik, Klinikum Bayreuth GmbH, CCC ER-EMN, Bayreuth, Germany.
Thomas Kuhn19 Karl-Olga-Krankenhaus, Stuttgart, Germany.
Christopher Wolf20 Medizinisches Zentrum Ulm, Ulm, Germany.
Hans-Walter Vollert21 Klinikum Friedrichshafen, Friedrichshafen, Germany.
Georg-Peter Breitbach22 Städtisches Klinikum Neunkirchen Gynäkologie und Geburtshilfe, Neunkirchen, Germany.
Wolfgang Janni23 Frauenklinik des Universitätsklinikums Ulm, Ulm, Germany.
Robert Landthaler24 Gynäkologische Praxis in der Kreisklinik Krumbach, Krumbach, Germany.
Andreas Kohls25 Evangelisches Krankenhaus Ludwigsfelde-Teltow, Ludwigsfelde, Germany.
Daniela Rezek26 Marien-Hospital Wesel, Wesel, Germany.
Thomas Noesslet27 Frauenklinik am Kreiskrankenhaus Hameln, Hameln, Germany.
Gunnar Fischer28 Landkreis Mittweida Krankenhaus gGmbH, Mittweida, Germany.
Stefan Henschen29 Johanniter Krankenhaus Genthin Stendal gGmbH, Stendal, Germany.
Thomas Praetz30 Caritas-Krankenhaus, Bad Mergentheim, Germany.
Volker Heyl31 Asklepios Paulinen Klinik, Wiesbaden, Germany.
Thorsten Kühn32 Frauenklinik, Städtische Kliniken, Esslingen am Neckar, Germany.
Thomas Krauss33 Frauenklinik Lippe-Detmold, Detmold, Germany.
Christoph Thomssen34 Frauenklinik, Martin Luther University, Halle-Wittenberg, Germany.
Andre Hohn35 Kreiskrankenhaus Rendsburg, Rendsburg, Germany.
Hans Tesch36 Onkologie Bethanien Frankfurt, Frankfurt, Germany.
Christoph Mundhenke37 Frauenklinik, Universitätsklinikum Schleswig-Holstein Campus Kiel, Kiel, Germany.
Alexander Hein1 Universitäts-Brustzentrum Franken, Frauenklinik, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-European Metropolitan area Nuremberg (CCC ER-EMN), Germany.
Claudia Rauh1 Universitäts-Brustzentrum Franken, Frauenklinik, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-European Metropolitan area Nuremberg (CCC ER-EMN), Germany.
Christian M Bayer1 Universitäts-Brustzentrum Franken, Frauenklinik, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-European Metropolitan area Nuremberg (CCC ER-EMN), Germany.
Adib Jacob38 Novartis Pharma GmbH, Nuremberg, Germany.
Katja Schmidt38 Novartis Pharma GmbH, Nuremberg, Germany.
Erik Belleville39 Clin-Sol GmbH, Würzburg, Germany.
Peyman Hadji40 Krankenhaus Nordwest, Klinik für Gynäkologie und Geburtshilfe, Frankfurt, Germany.
Sara Y Brucker3 Department für Frauengesundheit, Universitätsklinikum Tübingen, Eberhard-Karls-Universität, Tübingen, Germany.
Diethelm Wallwiener3 Department für Frauengesundheit, Universitätsklinikum Tübingen, Eberhard-Karls-Universität, Tübingen, Germany.
Sherko Kümmel41 Brustzentrum, Kliniken Essen Mitte, Evang. Huyssens-Stiftung/Knappschaft GmbH, Essen, Germany.
Matthias W Beckmann1 Universitäts-Brustzentrum Franken, Frauenklinik, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-European Metropolitan area Nuremberg (CCC ER-EMN), Germany.
Daniela Paepke42 Frauenklinik rechts der Isar, Technische Universität München, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreast cancer patients often use complementary and alternative medicine, but few prospectively collected data on the topic are available specifically for postmenopausal breast cancer patients. A large prospective study was therefore conducted within a noninterventional study in order to identify the characteristics of patients interested in integrative medicine.

methodsThe EvAluate-TM study is a prospective, multicenter noninterventional study in which treatment with the aromatase inhibitor letrozole was evaluated in postmenopausal women with hormone receptor-positive primary breast cancer. Between 2008 and 2009, 5045 postmenopausal patients were enrolled at 339 certified breast centers in Germany. As part of the data collection process, patients were asked at the baseline about their interest in and information needs relating to integrative medicine.

resultsOf the 5045 patients recruited, 3411 responded to the questionnaire on integrative medicine and took part in the analysis, 1583 patients expressed an interest in integrative medicine, and 1828 patients declared no interest. Relevant predictors of interest in integrative medicine were age, body mass index, tumor size, previous chemotherapy, and use of concomitant medications for other medical conditions. Interest in integrative medicine declined highly significantly ( P < .001) with age (<50 years, 74.1%; 50-60 years, 54.1%; >65 years, 38.0%). Patients in favor of integrative medicine were significantly less satisfied with the information received about individual treatments and antihormonal therapy. Patients with interest in integrative medicine were more often interested in rehabilitation and fitness, nutritional counseling, and additional support from self-help organizations. These women were mostly interested in receiving information about their disease and integrative medicine from a physician, rather than from other sources.

conclusionsThis study shows that a considerable proportion of postmenopausal breast cancer patients are interested in integrative medicine. Information about integrative medicine should therefore be provided as part of patient care for this group. It was found that receiving concomitant medication for other medical conditions is one of the main predictors for women not being interested in integrative medicine. This group of patients may need special attention and individualized information about integrative medicine. Additionally, most patients were interested in obtaining the relevant information from their doctor.

Indexed as

AgedAntineoplastic AgentsAromatase InhibitorsBreast NeoplasmsFemaleGermanyHumansIntegrative MedicineLetrozoleMiddle AgedNitrilesPostmenopauseProspective StudiesTriazolesAntineoplastic AgentsAromatase InhibitorsLetrozoleNitrilesTriazolesaromatase inhibitorbreast cancercomplementary and alternative medicineinformationintegrative medicineletrozoleoncologytherapy management

Identifiers

PMID27627986
PMCPMC5739129

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.