Evidence map›Paper›PMID 27627791›Full record

ArticleJournal of veterinary internal medicine2016

Survey of Two New (Kai 1 and Kai 2) and Other Blood Groups in Dogs of North America.

C C Euler, J H Lee, H Y Kim, K Raj, K Mizukami, U Giger

Abstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Evaluation of the utility and accuracy of body fluids containing red blood cells to determine canine and feline blood types.Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) · 2023
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Survey of Blood GroupsFrontiers in veterinary science · 2020
    Article
  10. Article
  11. Modified stall-side crossmatch for transfusions in horses.Journal of veterinary internal medicine · 2019
    Article
  12. Article
  13. Comparison of cross-matching method for detection of DEA 7 blood incompatibility.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2018
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

C C EulerSection of Medical Genetics, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA.
J H LeeDepartment of Physiology, College of Korean Medicine, Daegu Haany University, Daegu, South Korea.
H Y KimDepartment of Physiology, College of Korean Medicine, Daegu Haany University, Daegu, South Korea.
K RajSection of Medical Genetics, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA.
K MizukamiSection of Medical Genetics, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA.
U GigerSection of Medical Genetics, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA. giger@vet.upenn.edu.

Funding

Referral Ctr-Animal models of human genetic diseaseP40OD010939 · OD · UNIVERSITY OF PENNSYLVANIA · PI CASAL, MARGRET L · 2012 to 2023
$7.9M
NIH HHS P40 OD010939
6 · The paper itself

Abstract

backgroundBased upon serology, >10 canine blood group systems have been reported.

objectiveWe surveyed dogs for dog erythrocyte antigen (DEA) 1 and 2 new blood types (Kai 1 and Kai 2), and some samples also were screened for Dal and DEA 3, 4, and 7.

methodsBlood samples provided by owners, breeders, animal blood banks, and clinical laboratories were typed for DEA 1 by an immunochromatographic strip technique with a monoclonal antibody and analysis of band intensity. Both new antigens, the Dal and other DEAs (except DEA 7 by tube method), were assessed by a gel column method with either monoclonal or polyclonal antibodies. The same gel column method was applied for alloantibody detection.

resultsOf 503 dogs typed, 59.6% were DEA 1+ with 4% weakly, 10% moderately, and 45.6% strongly DEA 1+. Regarding Kai 1 and Kai 2, 94% were Kai 1+/Kai 2-, 5% were Kai 1-/Kai 2- and 1% were Kai 1-/Kai 2+, but none were Kai 1+/Kai 2+. There was no relationship between Kai 1/Kai 2 and other blood types tested. Plasma from DEA 1-, Kai 1-, Kai 2- dogs, or some combination of these contained no detectable alloantibodies against DEA 1 and Kai 1 or Kai, respectively. CONCLUSIONS AND CLINICAL IMPORTANCE: The new blood types, called Kai 1 and Kai 2, are unrelated to DEA 1, 3, 4, and 7 and Dal. Kai 1+/Kai 2- dogs were most commonly found in North America. The clinical relevance of Kai 1 and Kai 2 in canine transfusion medicine still needs to be elucidated.

Indexed as

AnimalsAntigens, SurfaceBlood Group AntigensBlood Grouping and CrossmatchingDogsErythrocytesNorth AmericaAntigens, SurfaceBlood Group AntigensAlloantibodiesBlood typesDog erythrocyte antigenHemolytic transfusion reactionTransfusion

Identifiers

PMID27627791
PMCPMC5032879

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.