Evidence map›Paper›PMID 27627195›Full record

ArticleAnnals of the New York Academy of Sciences2017

Machine learning approaches to personalize early prediction of asthma exacerbations.

Joseph Finkelstein, In Cheol Jeong

Abstract readComparative Study
In one paragraph

Article in Annals of the New York Academy of Sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Joseph FinkelsteinDepartment of Biomedical Informatics, Columbia University, New York, New York.
In Cheol JeongChronic Disease Informatics Program, Johns Hopkins University, Baltimore, Maryland.

Funding

MSHS Translational Science HubUL1TR001433 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WRIGHT, ROSALIND J · 2015 to 2019
$26.6M
Hypertension Telemanagement in African AmericansR01HL078579 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI FINKELSTEIN, JOSEPH E · 2004 to 2008
$3.7M
Evaluation of Home Automated Telemanagement in COPDR01HL071690 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI FINKELSTEIN, JOSEPH E · 2004 to 2008
$3.6M
EVALUATION OF HOME ASTHMA TELEMONITORING (HAT) IN ADULTSR01HL065355 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI FINKELSTEIN, JOSEPH E · 2000 to 2003
$1.4M
NCATS NIH HHS UL1 TR001433NHLBI NIH HHS R01 HL065355NHLBI NIH HHS R01 HL071690NHLBI NIH HHS R01 HL078579
6 · The paper itself

Abstract

Patient telemonitoring results in an aggregation of significant amounts of information about patient disease trajectory. However, the potential use of this information for early prediction of exacerbations in adult asthma patients has not been systematically evaluated. The aim of this study was to explore the utility of telemonitoring data for building machine learning algorithms that predict asthma exacerbations before they occur. The study dataset comprised daily self-monitoring reports consisting of 7001 records submitted by adult asthma patients during home telemonitoring. Predictive modeling included preparation of stratified training datasets, predictive feature selection, and evaluation of resulting classifiers. Using a 7-day window, a naive Bayesian classifier, adaptive Bayesian network, and support vector machines were able to predict asthma exacerbation occurring on day 8, with sensitivity of 0.80, 1.00, and 0.84; specificity of 0.77, 1.00, and 0.80; and accuracy of 0.77, 1.00, and 0.80, respectively. Our study demonstrated that machine learning techniques have significant potential in developing personalized decision support for chronic disease telemonitoring systems. Future studies may benefit from a comprehensive predictive framework that combines telemonitoring data with other factors affecting the likelihood of developing acute exacerbation. Approaches implemented for advanced asthma exacerbation prediction may be extended to prediction of exacerbations in patients with other chronic health conditions.

Indexed as

Decision Support Systems, ClinicalMachine LearningModels, BiologicalPrecision MedicineAdultAlgorithmsAsthmaBayes TheoremCombined Modality TherapyComputational BiologyDisease ProgressionElectronic Health RecordsHumansInternetMonitoring, PhysiologicPrognosisasthma exacerbationmachine learningpersonalized medicineprediction

Identifiers

PMID27627195
PMCPMC5266630

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.