ArticleJournal of biomedical optics2016
Hybridized wavefront shaping for high-speed, high-efficiency focusing through dynamic diffusive media.
Article in Journal of biomedical optics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Performance enhancement in wavefront shaping of multiply scattered light: a review.Journal of biomedical optics · 2024Review
- High-speed single-exposure time-reversed ultrasonically encoded optical focusing against dynamic scattering.Science advances · 2022Article
- Wavefront Shaping Concepts for Application in Optical Coherence Tomography-A Review.Sensors (Basel, Switzerland) · 2020Review
- High-speed alignment optimization of digital optical phase conjugation systems based on autocovariance analysis in conjunction with orthonormal rectangular polynomials.Journal of biomedical optics · 2018Article
- Time-reversed ultrasonically encoded optical focusing through highly scattering ex vivo human cataractous lenses.Journal of biomedical optics · 2018Article
- High-speed single-shot optical focusing through dynamic scattering media with full-phase wavefront shaping.Applied physics letters · 2017Article
- Focusing light through scattering media by polarization modulation based generalized digital optical phase conjugation.Applied physics letters · 2017Article
- Focusing light inside dynamic scattering media with millisecond digital optical phase conjugation.Optica · 2017Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
One of the prime limiting factors of optical imaging in biological applications is the diffusion of light by tissue, which prevents focusing at depths greater than the optical diffusion limit (typically ?1??mm). To overcome this challenge, wavefront shaping techniques that use a spatial light modulator (SLM) to correct the phase of the incident wavefront have recently been developed. These techniques are able to focus light through scattering media beyond the optical diffusion limit. However, the low speeds of typically used liquid crystal SLMs limit the focusing speed. Here, we present a method using a digital micromirror device (DMD) and an electro-optic modulator (EOM) to measure the scattering-induced aberrations, and using a liquid crystal SLM to apply the correction to the illuminating wavefront. By combining phase modulation from an EOM with the DMD’s ability to provide selective illumination, we exploit the DMD’s higher refresh rate for phase measurement. We achieved focusing through scattering media in less than 8 ms, which is sufficiently short for certain in vivo applications, as it is comparable to the speckle correlation time of living tissue.
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Registered trials
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