ReviewClinics (Sao Paulo, Brazil)2016
Expression of estrogen and progesterone receptors in astrocytomas: a literature review.
Review in Clinics (Sao Paulo, Brazil), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Oral Contraceptive and Glioma Risk: A Prospective Cohort Study and Meta-Analysis.Frontiers in public health · 2022Pooled it
- Evaluation of (Z)-endoxifen as a potential therapy for glioblastoma multiforme through computational and experimental analyses.Scientific reports · 2025Article
- Hormonal contraceptives in adolescence impact the neuroimmune environment of the medial prefrontal cortex and hippocampus in female rats.Brain, behavior, and immunity · 2025Article
- The global, regional, and national brain and CNS cancers burden and trends from 1990 to 2021.Scientific reports · 2025Article
- A Pan-Cancer Analysis of Age and Sex Differences in Cancer Incidence and Survival in the United States, 2001-2020.Cancers · 2025Article
- Effect of the Use of Gnrh Analogs in Low-Grade Cerebral Glioma.Children (Basel, Switzerland) · 2023Article
- Article
- Review
- From GWAS to drug screening: repurposing antipsychotics for glioblastoma.Journal of translational medicine · 2022Article
- Body mass index and glioma risk: A prospective multicenter study.Frontiers in endocrinology · 2022Article
- Progesterone suppresses the progression of colonic carcinoma by increasing the activity of the GADD45α/JNK/c‑Jun signalling pathway.Oncology reports · 2021Observational
- The Complex Interplay between Endocannabinoid System and the Estrogen System in Central Nervous System and Periphery.International journal of molecular sciences · 2021Review
- Acute post-partum vision loss due to pilocytic astrocytoma.American journal of ophthalmology case reports · 2020Article
- The Role of mPRδ and mPRε in Human Glioblastoma Cells: Expression, Hormonal Regulation, and Possible Clinical Outcome.Hormones & cancer · 2020Article
- Estrogen Receptor Expression in Glial Tumors of Iranian Patients: A Single Center Experience.Iranian journal of pathology · 2020Article
- A Coexisting Pilocytic Astrocytoma and a Prolactinoma: A Case Report of Collision Tumors and Literature Review.Cureus · 2019Article
- Testosterone Promotes Glioblastoma Cell Proliferation, Migration, and Invasion Through Androgen Receptor Activation.Frontiers in endocrinology · 2019Article
- Article
- Author Correction: Genetically engineered cerebral organoids model brain tumor formation.Nature methods · 2018Article
- Genetically engineered cerebral organoids model brain tumor formation.Nature methods · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gliomas are the most common type of primary central nervous system neoplasm. Astrocytomas are the most prevalent type of glioma and these tumors may be influenced by sex steroid hormones. A literature review for the presence of estrogen and progesterone receptors in astrocytomas was conducted in the PubMed database using the following MeSH terms: "estrogen receptor beta" OR "estrogen receptor alpha" OR "estrogen receptor antagonists" OR "progesterone receptors" OR "astrocytoma" OR "glioma" OR "glioblastoma". Among the 111 articles identified, 13 studies met our inclusion criteria. The majority of reports showed the presence of estrogen and progesterone receptors in astrocytomas. Overall, higher tumor grades were associated with decreased estrogen receptor expression and increased progesterone receptor expression.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.