Evidence map›Paper›PMID 27626313›Full record

ArticleOncotarget2016

Clinical outcome of intensity modulated radiotherapy for carcinoma showing thymus-like differentiation.

Fangfang Kong, Hongmei Ying, Ruiping Zhai, Chengrun Du, Shuang Huang, Junjun Zhou, Xiayun He, Chaosu Hu, Zhuoying Wang, Tuanqi Sun and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Inoperable CASTLE of the thyroid gland treated with radical radiotherapy with complete remission.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2021
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Fangfang KongDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, P.R. China.
Hongmei YingDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, P.R. China.
Ruiping ZhaiDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, P.R. China.
Chengrun DuDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, P.R. China.
Shuang HuangDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, P.R. China.
Junjun ZhouDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, P.R. China.
Xiayun HeDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, P.R. China.
Chaosu HuDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, P.R. China.
Zhuoying WangDepartment of Oncology, Shanghai Medical College, Fudan University, Shanghai, P.R. China.
Tuanqi SunDepartment of Oncology, Shanghai Medical College, Fudan University, Shanghai, P.R. China.
Qinghai JiDepartment of Oncology, Shanghai Medical College, Fudan University, Shanghai, P.R. China.
Shanghai Medical College of Fudan University · CNFudan University Shanghai Cancer Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the efficacy and toxicity of adjuvant intensity-modulated radiotherapy (IMRT) after surgery for carcinoma showing thymus-like differentiation (CASTLE).

methodsBetween September 2008 and June 2015, 14 CASTLE patients were retrospectively enrolled. The clinical features, treatment procedure and clinical outcomes were reviewed. All patients received postoperative IMRT. The radiation doses ranged from 56Gy/28 fractions to 66Gy/33 fractions. Treatment-related toxicities were graded by National Cancer Institute Common Toxicity Criteria (NCI-CTC) version 3.0.

resultsAfter a median follow-up period of 42 months, only one patient suffered local recurrence and distant metastasis. The most frequently seen acute toxicities were mucositis and dermatitis (grade 1-2). No grade 3-4 toxicities were observed.

conclusionsAlthough based upon a small series of consecutively treated patients, our study showed that adjuvant IMRT provides satisfactory local-regional control for CASTLE, with acceptable toxicities. Further studies are still warranted to clarify our findings.

Indexed as

Cell DifferentiationDose Fractionation, RadiationRadiotherapy, Intensity-ModulatedAdultCarcinomaFemaleHumansLymphatic MetastasisMaleMiddle AgedNeoplasm Recurrence, LocalRadiotherapy, AdjuvantRetrospective StudiesThyroidectomyThyroid NeoplasmsTime Factorscarcinoma showing thymus-like differentiationCASTLEIMRTintensity-modulated radiotherapyradiotherapy

Identifiers

PMID27626313
PMCPMC5348440
OpenAlexW2517729992

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.