Evidence map›Paper›PMID 27626198›Full record

ArticleCell metabolism2016

Mitochondrial Transfer from Astrocytes to Neurons following Ischemic Insult: Guilt by Association?

Michael V Berridge, Remy T Schneider, Melanie J McConnell

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cell metabolism, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

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  5. Mitochondria transfer in tissue homeostasis and diseases.International journal of biological sciences · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Michael V BerridgeMalaghan Institute of Medical Research, Wellington 6012, New Zealand. Electronic address: mberridge@malaghan.org.nz.
Remy T SchneiderMalaghan Institute of Medical Research, Wellington 6012, New Zealand; Victoria University of Wellington, Wellington 6140, New Zealand.
Melanie J McConnellVictoria University of Wellington, Wellington 6140, New Zealand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intercellular mitochondrial transfer has been shown in tumor models, following lung injury and in xenotransplants of leukemic cells, but trafficking between cells in the brain remains unexplored. A suggestion that mitochondria move from astrocytes to neurons in a model of ischemia in a recent article in Nature by Hayakawa et al. (2016) should be interpreted with caution.

Indexed as

AstrocytesMitochondriaBrainBrain IschemiaGuiltHumansNeurons

Identifiers

PMID27626198

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.