ReviewTemperature (Austin, Tex.)
Motion sickness, nausea and thermoregulation: The "toxic" hypothesis.
Review in Temperature (Austin, Tex.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 91 citations in OpenAlex.
- Reframing neuroergonomics in an evolutionary and active inference context.Frontiers in neuroergonomics · 2026Article
- Review
- The gut feeling in motion sickness.Communications biology · 2025Review
- Vestibular neurons link motion sickness, behavioural thermoregulation and metabolic balance in mice.Nature metabolism · 2025Article
- Article
- Evaluating proxies for motion sickness in rodent.IBRO neuroscience reports · 2023Article
- Vestibular CCK signaling drives motion sickness-like behavior in mice.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Hypergravity load-induced hyperglycemia occurs due to hypothermia and increased plasma corticosterone level in mice.The journal of physiological sciences : JPS · 2022Article
- Multi-Dimensional and Objective Assessment of Motion Sickness Susceptibility Based on Machine Learning.Frontiers in neurology · 2022Article
- Stroboscopic lighting with intensity synchronized to rotation velocity alleviates motion sickness gastrointestinal symptoms and motor disorders in rats.Frontiers in integrative neuroscience · 2022Article
- Article
- Using Positive Attribute Framing to Attenuate Nocebo Side Effects: A Cybersickness Study.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2021Article
- Electrogastrography in Autonomous Vehicles-An Objective Method for Assessment of Motion Sickness in Simulated Driving Environments.Sensors (Basel, Switzerland) · 2021Article
- Insights Into Acute and Delayed Cisplatin-Induced Emesis From a Microelectrode Array, Radiotelemetry and Whole-Body Plethysmography Study ofFrontiers in pharmacology · 2021Article
- Understanding vestibular-related physiological functions could provide clues on adapting to a new gravitational environment.The journal of physiological sciences : JPS · 2020Review
- Cross-coupling vestibular stimulation: motion sickness and the vestibulo-sympathetic reflex.Journal of neurology · 2017Article
- The efficacy of airflow and seat vibration on reducing visually induced motion sickness.Experimental brain research · 2017Article
- Brain Activation by HFrontiers in physiology · 2017Article
- Temperature in the spotlight of drug abuse research.Temperature (Austin, Tex.)Article
- Ondansetron and promethazine have differential effects on hypothermic responses to lithium chloride administration and to provocative motion in rats.Temperature (Austin, Tex.)Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Principal symptoms of motion sickness in humans include facial pallor, nausea and vomiting, and sweating. It is less known that motion sickness also affects thermoregulation, and the purpose of this review is to present and discuss existing data related to this subject. Hypothermia during seasickness was firstly noted nearly 150 years ago, but detailed studies of this phenomenon were conducted only during the last 2 decades. Motion sickness-induced hypothermia is philogenetically quite broadly expressed as besides humans, it has been reported in rats, musk shrews and mice. Evidence from human and animal experiments indicates that the physiological mechanisms responsible for the motion sickness-induced hypothermia include cutaneous vasodilation and sweating (leading to an increase of heat loss) and reduced thermogenesis. Together, these results suggest that motion sickness triggers highly coordinated physiological response aiming to reduce body temperature. Finally, we describe potential adaptive role of this response, and describe the benefits of using it as an objective measure of motion sickness-induced nausea.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.