Evidence map›Paper›PMID 27625746›Full record

ReviewWorld journal of diabetes2016

Assessment of the cardiovascular and gastrointestinal autonomic complications of diabetes.

Christina Brock, Birgitte Brock, Anne Grave Pedersen, Asbjørn Mohr Drewes, Niels Jessen, Adam D Farmer

Open access · diamondAbstract readReview
In one paragraph

Review in World journal of diabetes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Christina BrockChristina Brock, Anne Grave Pedersen, Asbjørn Mohr Drewes, Adam D Farmer, Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, DK-9000 Aalborg, Denmark.
Birgitte BrockChristina Brock, Anne Grave Pedersen, Asbjørn Mohr Drewes, Adam D Farmer, Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, DK-9000 Aalborg, Denmark.
Anne Grave PedersenChristina Brock, Anne Grave Pedersen, Asbjørn Mohr Drewes, Adam D Farmer, Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, DK-9000 Aalborg, Denmark.
Asbjørn Mohr DrewesChristina Brock, Anne Grave Pedersen, Asbjørn Mohr Drewes, Adam D Farmer, Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, DK-9000 Aalborg, Denmark.
Niels JessenChristina Brock, Anne Grave Pedersen, Asbjørn Mohr Drewes, Adam D Farmer, Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, DK-9000 Aalborg, Denmark.
Adam D FarmerChristina Brock, Anne Grave Pedersen, Asbjørn Mohr Drewes, Adam D Farmer, Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, DK-9000 Aalborg, Denmark.
University Hospitals of North Midlands NHS Trust · GBUniversity of Copenhagen · DKAalborg University Hospital · DKAarhus University · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global prevalence of diabetes mellitus is increasing; arguably as a consequence of changes in diet, lifestyle and the trend towards urbanization. Unsurprisingly, the incidence of both micro and macrovascular complications of diabetes mirrors this increasing prevalence. Amongst the complications with the highest symptom burden, yet frequently under-diagnosed and sub-optimally treated, is diabetic autonomic neuropathy, itself potentially resulting in cardiovascular autonomic neuropathy and gastrointestinal (GI) tract dysmotility. The aims of this review are fourfold. Firstly to provide an overview of the pathophysiological processes that cause diabetic autonomic neuropathy. Secondly, to discuss both the established and emerging cardiometric methods for evaluating autonomic nervous system function in vivo. Thirdly, to examine the tools for assessing pan-GI and segmental motility and finally, we will provide the reader with a summary of putative non-invasive biomarkers that provide a pathophysiological link between low-grade neuro inflammation and diabetes, which may allow earlier diagnosis and intervention, which in future may improve patient outcomes.

Indexed as

Autonomic nervous systemBiomarkersDiabetic neuropathyGastrointestinal dysmotilityNeuroinflammation

Identifiers

PMID27625746
PMCPMC4999648
OpenAlexW2516182231

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.