Evidence map›Paper›PMID 27625437›Full record

ArticleBiometrika2015

Selection and estimation for mixed graphical models.

Shizhe Chen, Daniela M Witten, Ali Shojaie

Abstract read
In one paragraph

Article in Biometrika, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Graphical Model Inference with Erosely Measured Data.Journal of the American Statistical Association · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Nonparametric Neighborhood Selection in Graphical Models.Journal of machine learning research : JMLR · 2022
    Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Nonparametric graphical model for counts.Journal of machine learning research : JMLR · 2020
    Article
  17. Article
  18. Article
  19. Article
  20. Gaussian and Mixed Graphical Models as (multi-)omics data analysis tools.Biochimica et biophysica acta. Gene regulatory mechanisms · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shizhe ChenDepartment of Biostatistics, University of Washington, Box 357232, Seattle, Washington 98195, U.S.A.
Daniela M WittenDepartment of Biostatistics, University of Washington, Box 357232, Seattle, Washington 98195, U.S.A.
Ali ShojaieDepartment of Biostatistics, University of Washington, Box 357232, Seattle, Washington 98195, U.S.A.

Funding

High-dimensional unsupervised learning, with applications to genomicsDP5OD009145 · OD · UNIVERSITY OF WASHINGTON · PI WITTEN, DANIELA · 2011 to 2015
$1.8M
Reconstructing Gene Regulatory Networks through Integration of Pertubation ScreenR21GM101719 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MICHAILIDIS, GEORGE · 2013 to 2014
$434k
NIGMS NIH HHS R21 GM101719NIH HHS DP5 OD009145
6 · The paper itself

Abstract

We consider the problem of estimating the parameters in a pairwise graphical model in which the distribution of each node, conditioned on the others, may have a different exponential family form. We identify restrictions on the parameter space required for the existence of a well-defined joint density, and establish the consistency of the neighbourhood selection approach for graph reconstruction in high dimensions when the true underlying graph is sparse. Motivated by our theoretical results, we investigate the selection of edges between nodes whose conditional distributions take different parametric forms, and show that efficiency can be gained if edge estimates obtained from the regressions of particular nodes are used to reconstruct the graph. These results are illustrated with examples of Gaussian, Bernoulli, Poisson and exponential distributions. Our theoretical findings are corroborated by evidence from simulation studies.

Indexed as

CompatibilityConditional likelihoodExponential familyHigh dimensionalityModel selection consistencyNeighbourhood selectionPairwise Markov random field

Identifiers

PMID27625437
PMCPMC5018402

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.