Evidence map›Paper›PMID 27625085›Full record

Trial reportChinese medical journal2016

Comparative Study between Robotic Total Thyroidectomy with Central Lymph Node Dissection via Bilateral Axillo-breast Approach and Conventional Open Procedure for Papillary Thyroid Microcarcinoma.

Qing-Qing He, Jian Zhu, Da-Yong Zhuang, Zi-Yi Fan, Lu-Ming Zheng, Peng Zhou, Lei Hou, Fang Yu, Yan-Ning Li, Lei Xiao and 2 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Chinese medical journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 9 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 9 syntheses or guidelines pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Postoperative pain outcomes following thyroidectomy: a systematic review and network meta-analysis of various surgical approaches.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
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  5. Conversion rates in robotic thyroid surgery: A systematic review and meta-analysis.The international journal of medical robotics + computer assisted surgery : MRCAS · 2022
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  10. Trial
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  15. HRQOL after endoscopic transaxillary gasless hemithyroidectomy.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2023
    Article
  16. [Clinical study of bilateral axillo-breast approach robot in obese women with thyroid cancer].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2023
    Article
  17. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Qing-Qing HeDepartment of Thyroid and Parathyroid Surgery, Jinan Military General Hospital of People's Liberation Army, Jinan, Shandong 250031, China.
Jian ZhuDepartment of Thyroid and Parathyroid Surgery, Jinan Military General Hospital of People's Liberation Army, Jinan, Shandong 250031, China.
Da-Yong ZhuangDepartment of Thyroid and Parathyroid Surgery, Jinan Military General Hospital of People's Liberation Army, Jinan, Shandong 250031, China.
Zi-Yi FanDepartment of Thyroid and Parathyroid Surgery, Jinan Military General Hospital of People's Liberation Army, Jinan, Shandong 250031, China.
Lu-Ming ZhengDepartment of Thyroid and Parathyroid Surgery, Jinan Military General Hospital of People's Liberation Army, Jinan, Shandong 250031, China.
Peng ZhouDepartment of Thyroid and Parathyroid Surgery, Jinan Military General Hospital of People's Liberation Army, Jinan, Shandong 250031, China.
Lei HouDepartment of Thyroid and Parathyroid Surgery, Jinan Military General Hospital of People's Liberation Army, Jinan, Shandong 250031, China.
Fang YuDepartment of Thyroid and Parathyroid Surgery, Jinan Military General Hospital of People's Liberation Army, Jinan, Shandong 250031, China.
Yan-Ning LiDepartment of Thyroid and Parathyroid Surgery, Jinan Military General Hospital of People's Liberation Army, Jinan, Shandong 250031, China.
Lei XiaoDepartment of Thyroid and Parathyroid Surgery, Jinan Military General Hospital of People's Liberation Army, Jinan, Shandong 250031, China.
Xue-Feng DongDepartment of Thyroid and Parathyroid Surgery, Jinan Military General Hospital of People's Liberation Army, Jinan, Shandong 250031, China.
Gao-Feng NiDepartment of Thyroid and Parathyroid Surgery, Jinan Military General Hospital of People's Liberation Army, Jinan, Shandong 250031, China.
Jinan Military General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA large proportion of the patients with papillary thyroid microcarcinoma are young women. Therefore, minimally invasive endoscopic thyroidectomy with central neck dissection (CND) emerged and showed well-accepted results with improved cosmetic outcome, accelerated healing, and comforting the patients. This study aimed to evaluate the safety and effectiveness of robotic total thyroidectomy with CND via bilateral axillo-breast approach (BABA), compared with conventional open procedure in papillary thyroid microcarcinoma.

methodsOne-hundred patients with papillary thyroid microcarcinoma from March 2014 to January 2015 in Jinan Military General Hospital of People's Liberation Army (PLA) were randomly assigned to robotic group or conventional open approach group (n = 50 in each group). The total operative time, estimated intraoperative blood loss, numbers of lymph node removed, visual analog scale (VAS), postoperative hospital stay time, complications, and numerical scoring system (NSS, used to assess cosmetic effect) were analyzed.

resultsThe robotic total thyroidectomy with CND via BABA was successfully performed in robotic group. There were no conversion from the robotic surgeries to open or endoscopic surgery. The subclinical central lymph node metastasis rate was 35%. The mean operative time of the robotic group was longer than that of the conventional open approach group (118.8 ± 16.5 min vs. 90.7 ± 10.3 min, P < 0.05). The study showed significant differences between the two groups in terms of the VASs (2.1 ± 1.0 vs. 3.8 ± 1.2, P < 0.05) and NSS (8.9 ± 0.8 vs. 4.8 ± 1.7, P < 0.05). The differences between the two groups in the estimated intraoperative blood loss, postoperative hospital stay time, numbers of lymph node removed, postoperative thyroglobulin levels, and complications were not statistically significant (all P > 0.05). Neither iatrogenic implantation nor metastasis occurred in punctured porous channel or chest wall in both groups. Postoperative cosmetic results were very satisfactory in the robotic group.

conclusionsRobotic total thyroidectomy with CND via BABA is safe and effective for Chinese patients with papillary thyroid microcarcinoma who worry about the neck scars.

Indexed as

AdultCarcinoma, PapillaryFemaleHumansLength of StayMaleMiddle AgedNeck DissectionOperative TimePostoperative PeriodRobotic Surgical ProceduresThyroglobulinThyroidectomyThyroid NeoplasmsThyroglobulin

Identifiers

PMID27625085
PMCPMC5022334
OpenAlexW3139543274

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.