Evidence map›Paper›PMID 27625064›Full record

ArticleBMJ open2016

Determinants of general practitioner's cancer-related gut feelings-a prospective cohort study.

Gé A Donker, Eva Wiersma, Lucas van der Hoek, Marianne Heins

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
8.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Understanding the role of GPs' gut feelings in diagnosing cancer in primary care: a systematic review and meta-analysis of existing evidence.The British journal of general practice : the journal of the Royal College of General Practitioners · 2020
    Pooled it
  4. Article
  5. Physicians' appraisal of parental concerns: a qualitative assessment.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025
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  15. GPs' use of gut feelings when assessing cancer risk: a qualitative study in UK primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021
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  16. Observational
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  20. Abdominal symptoms and cancer in the abdomen: prospective cohort study in European primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Gé A DonkerNIVEL Primary Care Database, Sentinel Practices, Utrecht, The Netherlands.
Eva WiersmaVU Medical Center, Amsterdam, The Netherlands.
Lucas van der HoekNIVEL Primary Care Database, Sentinel Practices, Utrecht, The Netherlands.
Marianne HeinsNIVEL Primary Care Database, Sentinel Practices, Utrecht, The Netherlands.
Netherlands Institute for Health Services Research · NLAmsterdam UMC Location VUmc · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGeneral practitioners (GPs) use gut feelings to diagnose cancer in an early stage, but little is known about its impact.

methodProspective cohort study of patients in 44 general practices throughout the Netherlands, from January 2010 until December 2013. GPs completed a questionnaire regarding gut feelings, patient and GP characteristics, if they noticed a cancer-related gut feeling during patient consultation. Follow-up questionnaires were sent 3 months later requesting information about the patient's diagnosis. χ(2), univariate and multivariate logistic regression and multilevel analyses were performed.

resultsA gut feeling (N=366) is most often triggered by weight loss (24%, N=85) and rare GP visits (22%, N=76), but all triggers were not predictive of cancer in a multivariate analysis. Most GPs (95%) acted immediately on the gut feeling, either referring to a specialist or by performing additional medical tests. The average positive predictive value of cancer-related gut feeling was 35%, and it increased with 2% for every year a patient becomes older, and with 3% for every year a GP becomes older.

conclusionsGP's gut feeling for cancer proves to be a useful tool in diagnosing cancer and its relative high predicting value increases if the GP is older or more experienced and when the patient is older. How can younger GPs be trained to increase the predictive value of their gut feeling?

Indexed as

General PractitionersIntuitionPractice Patterns, Physicians'AdolescentAdultAgedAged, 80 and overChildChild, PreschoolFemaleGastrointestinal TractHumansInfantInfant, NewbornJudgmentLogistic ModelsCancergeneral practicegut feelingintuitionprospective cohort study

Identifiers

PMID27625064
PMCPMC5030540
OpenAlexW2519674908

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.