Evidence map›Paper›PMID 27624940›Full record

ArticleThe Journal of biological chemistry2016

Selective Assembly of Na,K-ATPase α2β2 Heterodimers in the Heart: DISTINCT FUNCTIONAL PROPERTIES AND ISOFORM-SELECTIVE INHIBITORS.

Michael Habeck, Elmira Tokhtaeva, Yotam Nadav, Efrat Ben Zeev, Sean P Ferris, Randal J Kaufman, Elizabeta Bab-Dinitz, Jack H Kaplan, Laura A Dada, Zvi Farfel and 5 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Biomolecules · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. β subunit affects NaBiochemistry and biophysics reports · 2022
    Article
  11. Article
  12. Review
  13. Binding of cardiotonic steroids to NaProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  14. Review
  15. Article
  16. Article
  17. A possible mechanism for low affinity of silkworm NaJournal of bioenergetics and biomembranes · 2017
    Article
  18. Article
  19. How does pressure overload cause cardiac hypertrophy and dysfunction? High-ouabain affinity cardiac NaAmerican journal of physiology. Heart and circulatory physiology · 2017
    Review
  20. Identification of anti-viral activity of the cardenolides, NaToxicology and applied pharmacology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Michael HabeckFrom the Department of Biomolecular Sciences and.
Elmira Tokhtaevathe Department of Physiology, School of Medicine, UCLA and Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, California 90073.
Yotam NadavFrom the Department of Biomolecular Sciences and.
Efrat Ben ZeevIsrael National Centre for Personalized Medicine, Weizmann Institute of Science, Rehovoth 7610001, Israel.
Sean P Ferristhe Department of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Michigan 48109.
Randal J Kaufmanthe Department of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Michigan 48109.
Elizabeta Bab-DinitzFrom the Department of Biomolecular Sciences and.
Jack H Kaplanthe Department of Biochemistry and Molecular Genetics, University of Illinois, Chicago, Illinois 60607, and.
Laura A Dadathe Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611.
Zvi FarfelFrom the Department of Biomolecular Sciences and.
Daniel M TalFrom the Department of Biomolecular Sciences and.
Adriana KatzFrom the Department of Biomolecular Sciences and.
George Sachsthe Department of Physiology, School of Medicine, UCLA and Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, California 90073.
Olga Vaginthe Department of Physiology, School of Medicine, UCLA and Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, California 90073, olgav@ucla.edu.
Steven J D KarlishFrom the Department of Biomolecular Sciences and Steven.Karlish@weizmann.ac.il.
VA Greater Los Angeles Healthcare System · USUniversity of Michigan–Ann Arbor · USNorthwestern University · USTel Aviv University · ILUniversity of Illinois Chicago · USWeizmann Institute of Science · IL

Funding

PREDOCTORAL TRAINING IN GENETICST32GM007544 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MORAN, JOHN V. · 1985 to 2022
$11.3M
Role and Regulation of Sodium, Potasium ATPase in LungR37HL048129 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SZNAJDER, JACOB I · 2008 to 2017
$4.0M
Role of the Na K ATPase Beta 1 subunit in alveolar epithelial integrityR01HL113350 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DADA, LAURA ANDREA, VAGIN, OLGA · 2013 to 2016
$1.4M
The role of ArsS in gastric infection by Helicobacter pyloriR01DK105156 · NIDDK · BRENTWOOD BIOMEDICAL RESEARCH INSTITUTE · PI MARCUS, ELIZABETH A. · 2015 to 2018
$1.1M
Acid Adaptation Targets for Eradication of Helicobacter pyloriI01BX001006 · VA · VA GREATER LOS ANGELES HEALTHCARE SYSTEM · PI SACHS, GEORGE · 2011 to 2018
–
BLRD VA I01 BX001006NHLBI NIH HHS R01 HL113350NHLBI NIH HHS R37 HL048129NIDDK NIH HHS R01 DK105156NIGMS NIH HHS T32 GM007544
6 · The paper itself

Abstract

The Na,K-ATPase α

Indexed as

Adenosine TriphosphatasesAnimalsCation Transport ProteinsCell Adhesion Molecules, NeuronalDimerizationEnzyme InhibitorsHumansIsoenzymesKineticsMiceMyocardiumPotassiumSodiumSodium-Potassium-Exchanging ATPaseAdenosine TriphosphatasesAtp1a2 protein, mouseAtp1b2 protein, mouseCation Transport ProteinsCell Adhesion Molecules, NeuronalEnzyme InhibitorsIsoenzymesPotassiumSodiumSodium-Potassium-Exchanging ATPasealpha2beta2cardiomyocyteexcitation-contraction coupling (E-C coupling)isoform assemblyisoform-selective inhibitorskineticsmedicinal chemistrymolecular modelingNa+/K+-ATPase

Identifiers

PMID27624940
PMCPMC5087734
OpenAlexW2520393047

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.