Evidence map›Paper›PMID 27624855›Full record

ArticleVeterinary ophthalmology2017

Canine ocular onchocerciasis: a retrospective review of the diagnosis, treatment, and outcome of 16 cases in New Mexico (2011-2015).

Nancy Johnstone McLean, Kimberly Newkirk, Coenraad M Adema

Abstract read
In one paragraph

Article in Veterinary ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Zoonotic Ocular Onchocercosis byThe Yale journal of biology and medicine · 2021
    Review
  9. Article
  10. Complete mitochondrial genome ofMitochondrial DNA. Part B, Resources · 2021
    Article
  11. Article
  12. First report ofParasitology · 2020
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Nancy Johnstone McLeanOphthalmology, VCA Veterinary Care Animal Hospital and Referral Center, 9901 Montgomery Boulevard NE, 87111, Albuquerque, NM, USA.
Kimberly NewkirkAnatomic Pathobiology, Biomedical and Diagnostic Sciences, University of Tennessee, 2407 River Drive, Room A205, 37996-4542, Knoxville, TN, USA.
Coenraad M AdemaCenter for Evolutionary and Theoretical Immunology, University of New Mexico, Castetter Hall Biology MSC03 2020, 87112-0001, Albuquerque, NM, USA.
California Animal Hospital · USUniversity of New Mexico · USUniversity of Tennessee at Knoxville · US

Funding

Pilot Project ProgramP30GM110907 · NIGMS · UNIVERSITY OF NEW MEXICO · PI MILLER, ROBERT D · 2014 to 2018
$5.4M
COBRE Center for Evolutionary and Theoretical ImmunologyP20GM103452 · NIGMS · UNIVERSITY OF NEW MEXICO · PI LOKER, ERIC SAMUEL · 2012 to 2013
$4.2M
NIGMS NIH HHS P20 GM103452NIGMS NIH HHS P30 GM110907
6 · The paper itself

Abstract

objectiveTo describe the clinical exam findings, treatment and outcomes of 16 dogs diagnosed with ocular onchocerciasis in New Mexico. MATERIALS AND

methodsRecords of dogs diagnosed by the primary author were reviewed (2011-2015). Records that were accessible and included a diagnosis of Onchocerca lupi by histopathologic or molecular identification of the nematode were included.

resultsSixteen cases were included. 3/16 dogs were treated with year-round heartworm prophylaxis prior to infection. Clinical exam findings included conjunctival hyperemia and/or episcleral injection (16/16), focal subconjunctival mass(es) (14/16), retinal detachment (7/16), corneal edema (4/16), chemosis (3/16), corneal opacity (2/16), exophthalmia (1/16), glaucoma (1/16), strabismus (1/16), blepharospasm (1/16), and vitreal degeneration (1/16). Ocular involvement was unilateral in 7/16 dogs and bilateral in 9/16 dogs. The diagnosis was confirmed via histologic identification of the nematodes and/or PCR. Treatment consisted of medical management or a combination medical and surgical management. Known or suspected recurrence of disease was documented in 10 dogs.

conclusionsCanine ocular onchocerciasis is endemic in New Mexico. Histopathology and molecular identification are useful diagnostic tools. Medical management alone was successful in many cases.

Indexed as

AnimalsDog DiseasesDogsFemaleMaleNew MexicoOnchocercaOnchocerciasis, OcularRetrospective StudiescanineNew MexicoocularOnchocerca lupionchocercosisparasite

Identifiers

PMID27624855
PMCPMC5348283
OpenAlexW2519826029

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.