ArticleNature communications2016
The electrophotonic silicon biosensor.
Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Precision Design of Single-Atom Catalysts for High-Performance Biosensors.Chemical record (New York, N.Y.) · 2026Pooled it
- Using Triazabutadienes as a Protected Source of Diazonium Cations to Facilitate Electrografting to a Variety of Conductive Surfaces.Langmuir : the ACS journal of surfaces and colloids · 2025Article
- Review
- Electronic Transport Modulation in Ultrastrained Silicon Nanowire Devices.ACS applied materials & interfaces · 2024Article
- Harnessing DNA Nanotechnology and Chemistry for Applications in Photonics and Electronics.Bioconjugate chemistry · 2023Review
- Biofunctionalization of Multiplexed Silicon Photonic Biosensors.Biosensors · 2022Review
- Recent Advancements in Nanobiosensors: Current Trends, Challenges, Applications, and Future Scope.Biosensors · 2022Review
- Dielectrophoresis: An Approach to Increase Sensitivity, Reduce Response Time and to Suppress Nonspecific Binding in Biosensors?Biosensors · 2022Review
- Review
- Bioimpedance Sensing of Implanted Stent Occlusions: Smart Stent.Biosensors · 2022Article
- BeyondACS photonics · 2022Article
- Electro-optically modulated lossy-mode resonance.Nanophotonics (Berlin, Germany) · 2022Article
- Photoluminescence enhancement by deterministically site-controlled, vertically stacked SiGe quantum dots.Scientific reports · 2021Article
- Review
- Recent advances in environmental and clinical analysis using microring resonator-based sensors.Current opinion in environmental science & health · 2019Article
- Developments in Transduction, Connectivity and AI/Machine Learning for Point-of-Care Testing.Sensors (Basel, Switzerland) · 2019Article
- On the origin of second harmonic generation in silicon waveguides with silicon nitride cladding.Scientific reports · 2019Article
- Methodologies for "Wiring" Redox Proteins/Enzymes to Electrode Surfaces.Chemistry (Weinheim an der Bergstrasse, Germany) · 2018Review
- Dual-Mode Electro-Optical Techniques for Biosensing Applications: A Review.Sensors (Basel, Switzerland) · 2017Review
- Degradation of silicon photonic biosensors in cell culture media: analysis and prevention.Biomedical optics express · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The emergence of personalized and stratified medicine requires label-free, low-cost diagnostic technology capable of monitoring multiple disease biomarkers in parallel. Silicon photonic biosensors combine high-sensitivity analysis with scalable, low-cost manufacturing, but they tend to measure only a single biomarker and provide no information about their (bio)chemical activity. Here we introduce an electrochemical silicon photonic sensor capable of highly sensitive and multiparameter profiling of biomarkers. Our electrophotonic technology consists of microring resonators optimally n-doped to support high Q resonances alongside electrochemical processes in situ. The inclusion of electrochemical control enables site-selective immobilization of different biomolecules on individual microrings within a sensor array. The combination of photonic and electrochemical characterization also provides additional quantitative information and unique insight into chemical reactivity that is unavailable with photonic detection alone. By exploiting both the photonic and the electrical properties of silicon, the sensor opens new modalities for sensing on the microscale.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.