Trial reportScientific reports2016
Replicating Cardiovascular Condition-Birth Month Associations.
Trial report in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Artificial intelligence in the management of metabolic disorders: a comprehensive review.Journal of endocrinological investigation · 2025Review
- Capacity Planning (Capital, Staff and Costs) of Inpatient Maternity Services: Pitfalls for the Unwary.International journal of environmental research and public health · 2025Article
- No evidence for an association between in utero Ramadan exposure and mean arterial pressure and random blood glucose in adulthood: evidence from SEACO in Malaysia.Journal of nutritional science · 2025Article
- Uncovering Important Diagnostic Features for Alzheimer's, Parkinson's and Other Dementias Using Interpretable Association Mining Methods.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing · 2025Article
- Determining the Importance of Clinical Modalities for NeuroDegenerative Disorders and Risk of Patient Injury Using Machine Learning and Survival Analysis.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2025Article
- Are season of birth, climate, and parental age predictors of adult temperament, character, anhedonia, suicidality, and self-harm?Frontiers in psychiatry · 2025Article
- Date of birth and the incidence of acute ischemic stroke in Hungary.Revista de neurologia · 2022Article
- Harnessing electronic health records to study emerging environmental disasters: a proof of concept with perfluoroalkyl substances (PFAS).NPJ digital medicine · 2021Article
- Early detection of type 2 diabetes mellitus using machine learning-based prediction models.Scientific reports · 2020Article
- Birth month, birth season, and overall and cardiovascular disease mortality in US women: prospective cohort study.BMJ (Clinical research ed.) · 2019Article
- Applied Veterinary Informatics: Development of a Semantic and Domain-Specific Method to Construct a Canine Data Repository.Scientific reports · 2019Article
- Development and validation of the PEPPER framework (Prenatal Exposure PubMed ParsER) with applications to food additives.Journal of the American Medical Informatics Association : JAMIA · 2018Article
- Cardiovascular Disease Risk Varies by Birth Month in Canines.Scientific reports · 2018Article
- Uncovering exposures responsible for birth season - disease effects: a global study.Journal of the American Medical Informatics Association : JAMIA · 2018Article
- Multifactorial analysis of the stochastic epigenetic variability in cord blood confirmed an impact of common behavioral and environmental factors but not of in vitro conception.Clinical epigenetics · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Independent replication is vital for study findings drawn from Electronic Health Records (EHR). This replication study evaluates the relationship between seasonal effects at birth and lifetime cardiovascular condition risk. We performed a Season-wide Association Study on 1,169,599 patients from Mount Sinai Hospital (MSH) to compute phenome-wide associations between birth month and CVD. We then evaluated if seasonal patterns found at MSH matched those reported at Columbia University Medical Center. Coronary arteriosclerosis, essential hypertension, angina, and pre-infarction syndrome passed phenome-wide significance and their seasonal patterns matched those previously reported. Atrial fibrillation, cardiomyopathy, and chronic myocardial ischemia had consistent patterns but were not phenome-wide significant. We confirm that CVD risk peaks for those born in the late winter/early spring among the evaluated patient populations. The replication findings bolster evidence for a seasonal birth month effect in CVD. Further study is required to identify the environmental and developmental mechanisms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.