ArticleBioorganic & medicinal chemistry2016
New potently bioactive alkaloids from Crinum erubescens.
Article in Bioorganic & medicinal chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 39 citations in OpenAlex.
- Cripowellins PauseMolecules (Basel, Switzerland) · 2023Article
- The Phytochemistry and Pharmacology ofMolecules (Basel, Switzerland) · 2022Review
- Lycorine Alkaloid andMolecules (Basel, Switzerland) · 2022Article
- Antimalarial Natural Products.Progress in the chemistry of organic natural products · 2022Article
- Alkaloid Profiling and Cholinesterase Inhibitory Potential ofPlants (Basel, Switzerland) · 2021Article
- Advances in the Chemical and Biological Characterization of Amaryllidaceae Alkaloids and Natural Analogues Isolated in the Last Decade.Molecules (Basel, Switzerland) · 2020Review
- Biosynthesis and Biological Activities of Newly Discovered Amaryllidaceae Alkaloids.Molecules (Basel, Switzerland) · 2020Review
- Amaryllidaceae alkaloids with anti-Trypanosoma cruzi activity.Parasites & vectors · 2020Article
- Antiproliferative Effects of Alkaloids from the Bulbs ofEvidence-based complementary and alternative medicine : eCAM · 2020Article
- Alkaloids from Plants with Antimalarial Activity: A Review of Recent Studies.Evidence-based complementary and alternative medicine : eCAM · 2020Review
- Antiplasmodial natural products: an update.Malaria journal · 2019Review
- Article
- Isolation, structure elucidation, and synthesis of antiplasmodial quinolones from Crinum firmifolium.Bioorganic & medicinal chemistry · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Antimalarial bioassay-guided fractionation of the swamp lily Crinum erubescens led to the isolation of four compounds with potent antiplasmodial activity. Compounds 1 and 2 were determined from their spectroscopic data to be the known pesticidal compound cripowellin A and the known pesticidal and antiproliferative compound cripowellin B. 1D and 2D-NMR techniques were used to determine the identities of 3 and 4 as the new compounds cripowellin C and D. A fifth compound was identified as the known alkaloid hippadine, which was inactive against Plasmodium falciparum. The antiplasmodial IC
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.