ArticleJournal of biophotonics2017
Laser thermal therapy monitoring using complex differential variance in optical coherence tomography.
Article in Journal of biophotonics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Temperature-induced hemoglobin dynamics: oxygenation-dependent evolution of hemoglobin spectral response in the near-infrared.Biophotonics discovery · 2026Article
- Image-Based Monitoring of Thermal Ablation.Bioengineering (Basel, Switzerland) · 2025Review
- Radiation-induced alterations in multi-layered, in-vitro skin models detected by optical coherence tomography and histological methods.PloS one · 2023Article
- Double-Clad Fiber-Based Multifunctional Biosensors and Multimodal Bioimaging Systems: Technology and Applications.Biosensors · 2022Review
- Real-time co-localized OCT surveillance of laser therapy using motion corrected speckle decorrelation.Biomedical optics express · 2020Article
- Noise and bias in optical coherence tomography intensity signal decorrelation.OSA continuum · 2020Article
- Molecular Antenna-Sensitized Upconversion Nanoparticle for Temperature Monitored Precision Photothermal Therapy.International journal of nanomedicine · 2020Article
- Balloon catheter-based radiofrequency ablation monitoring in porcine esophagus using optical coherence tomography.Biomedical optics express · 2019Article
- Noninvasive Assessment of Corneal Crosslinking With Phase-Decorrelation Optical Coherence Tomography.Investigative ophthalmology & visual science · 2019Article
- Association of Electrochemical Therapy With Optical, Mechanical, and Acoustic Impedance Properties of Porcine Skin.JAMA facial plastic surgery · 2017Article
- Assessment of the radiofrequency ablation dynamics of esophageal tissue with optical coherence tomography.Journal of biomedical optics · 2017Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Conventional thermal therapy monitoring techniques based on temperature are often invasive, limited by point sampling, and are indirect measures of tissue injury, while techniques such as magnetic resonance and ultrasound thermometry are limited by their spatial resolution. The visualization of the thermal coagulation zone at high spatial resolution is particularly critical to the precise delivery of thermal energy to epithelial lesions. In this work, an integrated thulium laser thermal therapy monitoring system was developed based on complex differential variance (CDV), which enables the 2D visualization of the dynamics of the thermal coagulation process at high spatial and temporal resolution with an optical frequency domain imaging system. With proper calibration to correct for noise, the CDV-based technique was shown to accurately delineate the thermal coagulation zone, which is marked by the transition from high CDV upon heating to a significantly reduced CDV once the tissue is coagulated, in 3 different tissue types ex vivo: skin, retina, and esophagus. The ability to delineate thermal lesions in multiple tissue types at high resolution opens up the possibility of performing microscopic image-guided procedures in a vast array of epithelial applications ranging from dermatology, ophthalmology, to gastroenterology and beyond.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.