ArticleChimerism2015
Microchimerism of male origin in a cohort of Danish girls.
Article in Chimerism, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 28 citations in OpenAlex.
- Identifying Key Questions and Challenges in Microchimerism Biology.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Sex, male origin microchimerism, and mortality in a Danish cohort.European journal of epidemiology · 2025Article
- Transplacental cancer transmission: a comprehensive review focusing on mechanisms, challenges, and maternal-fetal outcomes.Journal of the Turkish German Gynecological Association · 2025Article
- The duality of microchimerism and cancer in parous women: a review and evolutionary perspective.Seminars in immunopathology · 2025Review
- Maternal microchimeric cell trafficking and its biological consequences depend on the onset of inflammation at the feto-maternal interface.Seminars in immunopathology · 2025Review
- The Microchimerism Literature Atlas.Bioinformatics and biology insights · 2025Article
- Quantification of Female Chimeric Cells in the Tonsils of Male Children and Their Determinants.Cells · 2023Article
- Male origin microchimerism and brain cancer: a case-cohort study.Journal of cancer research and clinical oncology · 2023Article
- Article
- Feto-maternal microchimerism: Memories from pregnancy.iScience · 2022Review
- Grandmaternal cells in cord blood.EBioMedicine · 2021Article
- Fetal microchimerism and implications for maternal health.Obstetric medicine · 2020Review
- Low prevalence of male microchimerism in women with Mayer-Rokitansky-Küster-Hauser syndrome.Human reproduction (Oxford, England) · 2019Observational
- Fetal microchimerism in human brain tumors.Brain pathology (Zurich, Switzerland) · 2018Article
- Immunological implications of pregnancy-induced microchimerism.Nature reviews. Immunology · 2017Review
- Mosaicism in health and disease - clones picking up speed.Nature reviews. Genetics · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Male microchimerism, the presence of a small number of male cells, in women has been attributed to prior pregnancies. However, male microchimerism has also been reported in women with only daughters, in nulliparous women and prepubertal girls suggesting that other sources of male microchimerism must exist. The aim of the present study was to examine the presence of male microchimerism in a cohort of healthy nulliparous Danish girls aged 10-15 y using DNA extracted from cells from whole blood (buffy coats) and report the association with potential sources of male cells. A total of 154 girls were studied of which 21 (13.6%) tested positive for male microchimerism. There was a tendency that girls were more likely to test positive for male microchimerism if their mothers previously had received transfusion, had given birth to a son or had had a spontaneous abortion. Furthermore, the oldest girls were more likely to test positive for male microchimerism. However, less than half of microchimerism positivity was attributable to these factors. In conclusion, data suggest that male microchimerism in young girls may originate from an older brother either full born or from a discontinued pregnancy or from transfusion during pregnancy. We speculate that sexual intercourse may be important but other sources of male cells likely exist in young girls.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.