ArticleeLife2016
Hypothalamic transcriptomes of 99 mouse strains reveal trans eQTL hotspots, splicing QTLs and novel non-coding genes.
Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
32 citing papers in PubMed.
- Divergent jejunal cis- and trans-eQTLs and their microbiome associations following a diet lacking mineral phosphorus supplements in laying hens.BMC genomics · 2026Article
- Inference of spatial chromatin accessibility via integration of spatial transcriptomics and single-cell multi-omics data.Nature communications · 2026Article
- Saturating the eQTL map in Drosophila: Genome-wide patterns of cis and trans regulation of transcriptional variation in outbred populations.Cell genomics · 2025Article
- Identification of Expression Quantitative Trait Loci (eQTL) for Adipose-Specific Regulatory Mechanisms in Hanwoo (Korean Cattle).Animals : an open access journal from MDPI · 2025Article
- Hybrids reveal accessible chromatinbioRxiv : the preprint server for biology · 2025Article
- Differing Genetics of Saline and Cocaine Self-Administration in the Hybrid Mouse Diversity Panel.Genes, brain, and behavior · 2025Article
- Differing genetics of saline and cocaine self-administration in the hybrid mouse diversity panel.bioRxiv : the preprint server for biology · 2025Article
- ADELLE: A global testing method for trans-eQTL mapping.PLoS genetics · 2025Article
- Genetic pathways regulating the longitudinal acquisition of cocaine self-administration in a panel of inbred and recombinant inbred mice.Cell reports · 2023Article
- Conserved multi-tissue transcriptomic adaptations to exercise training in humans and mice.Cell reports · 2023Article
- The regulatory landscape of multiple brain regions in outbred heterogeneous stock rats.Nucleic acids research · 2022Article
- Extreme phenotypic diversity in operant response to intravenous cocaine or saline infusion in the hybrid mouse diversity panel.Addiction biology · 2022Article
- Integration of feeding behavior by the liver circadian clock reveals network dependency of metabolic rhythms.Science advances · 2021Article
- Where Are the Disease-Associated eQTLs?Trends in genetics : TIG · 2021Review
- Alternative Splicing Dynamics of the Hypothalamus-Pituitary-Ovary Axis During Pubertal Transition in Gilts.Frontiers in genetics · 2021Article
- Article
- Systematic identification ofeLife · 2020Article
- The GeneG3 (Bethesda, Md.) · 2020Article
- mRNA Metabolism in Cardiac Development and Disease: Life After Transcription.Physiological reviews · 2020Review
- Sex-Dimorphic Behavioral Alterations and Altered Neurogenesis in U12 Intron Splicing-DefectiveInternational journal of molecular sciences · 2019Article
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
Previous studies had shown that the integration of genome wide expression profiles, in metabolic tissues, with genetic and phenotypic variance, provided valuable insight into the underlying molecular mechanisms. We used RNA-Seq to characterize hypothalamic transcriptome in 99 inbred strains of mice from the Hybrid Mouse Diversity Panel (HMDP), a reference resource population for cardiovascular and metabolic traits. We report numerous novel transcripts supported by proteomic analyses, as well as novel non coding RNAs. High resolution genetic mapping of transcript levels in HMDP, reveals both
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Registered trials
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