Evidence map›Paper›PMID 27623009›Full record

ArticleeLife2016

Ciliary transcription factors and miRNAs precisely regulate Cp110 levels required for ciliary adhesions and ciliogenesis.

Peter Walentek, Ian K Quigley, Dingyuan I Sun, Umeet K Sajjan, Christopher Kintner, Richard M Harland

Open access · goldAbstract read
In one paragraph

Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
7.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 75 citations in OpenAlex.

  1. Review
  2. Taking Down the Primary Cilium: Pathways for Disassembly in Differentiating Cells.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Formation and function of multiciliated cells.The Journal of cell biology · 2024
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Ciliogenesis membrane dynamics and organization.Seminars in cell & developmental biology · 2023
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Peter WalentekDivision of Genetics, Genomics and Development, Center for Integrative Genomics, Department of Molecular and Cell Biology, University of California, Berkeley, United States.ORCID http://orcid.org/0000-0002-2332-6068
Ian K QuigleyMolecular Neurobiology Laboratory, Salk Institute for Biological Studies, La Jolla, United States.ORCID http://orcid.org/0000-0003-0075-8324
Dingyuan I SunDivision of Genetics, Genomics and Development, Center for Integrative Genomics, Department of Molecular and Cell Biology, University of California, Berkeley, United States.
Umeet K SajjanDivision of Genetics, Genomics and Development, Center for Integrative Genomics, Department of Molecular and Cell Biology, University of California, Berkeley, United States.
Christopher KintnerMolecular Neurobiology Laboratory, Salk Institute for Biological Studies, La Jolla, United States.
Richard M HarlandDivision of Genetics, Genomics and Development, Center for Integrative Genomics, Department of Molecular and Cell Biology, University of California, Berkeley, United States.ORCID http://orcid.org/0000-0001-8247-4880
Innovative Genomics Institute · USSalk Institute for Biological Studies · US

Funding

Viral Vector Core (VVC)P30CA014195 · NCI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Ye Zheng · 1985 to 2026
$82.8M
SynthesisP30DK072517 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VERKMAN, ALAN S · 2005 to 2022
$18.1M
Gene Expression in Amphibian DevlopementR01GM042341 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI HARLAND, RICHARD M · 1988 to 2016
$5.7M
Molecular Bases of Cilia OrientationR01GM076507 · NIGMS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI KINTNER, CHRISTOPHER ROBERT · 2005 to 2017
$4.9M
A Zeiss Elyra S1 Structured Illumination Microscope for the Biological Imaging FaS10OD018136 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI RUZIN, STEVEN EARL · 2014 to 2014
$600k
Molecular mechanisms of mucociliary function and airway clearanceK99HL127275 · NHLBI · UNIVERSITY OF CALIFORNIA BERKELEY · PI WALENTEK, PETER · 2016 to 2017
$268k
NCI NIH HHS P30 CA014195NHLBI NIH HHS K99 HL127275NIDDK NIH HHS P30 DK072517NIGMS NIH HHS R01 GM042341NIGMS NIH HHS R01 GM076507NIH HHS S10 OD018136
6 · The paper itself

Abstract

Upon cell cycle exit, centriole-to-basal body transition facilitates cilia formation. The centriolar protein Cp110 is a regulator of this process and cilia inhibitor, but its positive roles in ciliogenesis remain poorly understood. Using

Indexed as

cell biologycentrioleciliadevelopmental biologyfocal adhesionFoxj1humanMCIDASmiR-34miR-449mucociliary epitheliaRFX2stem cellsxenopus

Identifiers

PMID27623009
PMCPMC5045295
OpenAlexW2519381838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.