ArticlePloS one2016
Differences in Biofilm Mass, Expression of Biofilm-Associated Genes, and Resistance to Desiccation between Epidemic and Sporadic Clones of Carbapenem-Resistant Acinetobacter baumannii Sequence Type 191.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 48 citations in OpenAlex.
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- Linalool exhibits potent antibacterial and anti-biofilm activity against carbapenem-resistant Acinetobacter baumannii.Scientific reports · 2026Article
- Asiatic acid disrupts biofilm formation and shows additive effect with antibiotic against Acinetobacter baumannii.AMB Express · 2026Article
- Phenylacetic acid mediatesMicrobiology (Reading, England) · 2026Article
- Preliminary Assessment ofGenes · 2025Article
- Targeting PilA in Acinetobacter baumannii: A Computational Approach for Anti-Virulent Compound Discovery.Molecular biotechnology · 2025Article
- Evaluation of Cinnamon Essential Oil and Its Emulsion on Biofilm-Associated Components ofAntibiotics (Basel, Switzerland) · 2025Article
- Understanding the clinical and molecular epidemiological characteristics of carbapenem-resistant Acinetobacter baumannii infections within intensive care units of three teaching hospitals.Annals of clinical microbiology and antimicrobials · 2025Article
- Genomic insights into biofilm-associated virulence in extensively drug-resistantCurrent research in microbial sciences · 2025Article
- Investigation the effects of silver nanoparticles and gold nanoparticles on expression ofIranian journal of microbiology · 2022Article
- Article
- Convergence of Biofilm Formation and Antibiotic Resistance inFrontiers in medicine · 2022Review
- ppGpp signaling plays a critical role in virulence ofVirulence · 2021Article
- Relationship between the Biofilm-Forming Capacity and Antimicrobial Resistance in ClinicalMicroorganisms · 2021Article
- Therapeutic Effects of Inhibitor ofInternational journal of molecular sciences · 2021Article
- Carboxy-Terminal Processing Protease Controls Production of Outer Membrane Vesicles and Biofilm inMicroorganisms · 2021Article
- Interactions of plasma-activated water with biofilms: inactivation, dispersal effects and mechanisms of action.NPJ biofilms and microbiomes · 2021Review
- Phenotypic and Genotypic Characteristics of Biofilm Formation in Clinical Isolates ofInfection and drug resistance · 2021Article
- Recent Advances in the Pursuit of an EffectivePathogens (Basel, Switzerland) · 2020Review
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Understanding the biology behind the epidemicity and persistence of Acinetobacter baumannii in the hospital environment is critical to control outbreaks of infection. This study investigated the contributing factors to the epidemicity of carbapenem-resistant A. baumannii (CRAB) sequence type (ST) 191 by comparing the differences in biofilm formation, expression of biofilm-associated genes, and resistance to desiccation between major epidemic (n = 16), minor epidemic (n = 12), and sporadic (n = 12) clones. Biofilm mass was significantly greater in the major epidemic than the minor epidemic and sporadic clones. Major and minor epidemic clones expressed biofilm-associated genes, abaI, bap, pgaABCD, and csuA/BABCDE, higher than the sporadic clones in sessile conditions. The csuC, csuD, and csuE genes were more highly expressed in the major epidemic than minor epidemic clones. Interestingly, minor epidemic clones expressed more biofilm-associated genes than the major epidemic clone under planktonic conditions. Major epidemic clones were more resistant to desiccation than minor epidemic and sporadic clones on day 21. In conclusion, the epidemic CRAB ST191 clones exhibit a higher capacity to form biofilms, express the biofilm-associated genes under sessile conditions, and resist desiccation than sporadic clones. These phenotypic and genotypic characteristics of CRAB ST191 may account for the epidemicity of specific CRAB ST191 clones in the hospital.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.