ReviewHerz2017
Platypnea-orthodeoxia syndrome : Orthostatic dyspnea and possible pathophysiological substrates.
Review in Herz, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- Horizontal Heart Orientation as a Mechanistic Contributor to Platypnea-Orthodeoxia Syndrome in Patent Foramen Ovale.Clinical case reports · 2026Article
- High-Flow Oxygen Therapy to Support Inpatient Pulmonary Rehabilitation During Very Severe Hepatopulmonary Syndrome Recovery Post Liver Transplant: A Case Report.Clinical case reports · 2025Article
- When hypoxemia does not respond to oxygen therapy: a case of platypnea-orthodeoxia syndrome.Archivos de cardiologia de Mexico · 2024Article
- Platypnea-Orthodeoxia Syndrome Caused by Patent Foramen Ovale with Right-To-Left Shunt.The American journal of case reports · 2023Article
- A case report of platypnea-orthodeoxia syndrome: A rare condition found during diagnostic workup of a patient with embolic stroke of undetermined sources.eNeurologicalSci · 2022Article
- Severe Pneumonia Caused by SARS-CoV-2: A Novel Cause of Platypnoea-Orthodeoxia Syndrome.European journal of case reports in internal medicine · 2022Article
- Platypnea-orthodeoxia syndrome in a postoperative patient: a case report.Journal of medical case reports · 2021Article
- Patent foramen ovale revealed by COVID-19 pneumonia.BMC pulmonary medicine · 2021Article
- Retraction: De Vecchis, R., et al. Platypnea-Orthodeoxia Syndrome: Multiple Pathophysiological Interpretations of a Clinical Picture Primarily Consisting of Orthostatic Dyspnea.Journal of clinical medicine · 2021Article
- When sitting suffocates: a rare cause of platypnoea-orthodeoxia syndrome.Breathe (Sheffield, England) · 2020Article
- Platypnoea-orthodeoxia syndrome induced by short-term weight loss: a case series.European heart journal. Case reports · 2020Article
- Platypnea-orthodeoxia after fibrotic evolution of SARS-CoV-2 interstitial pneumonia. A case report.Acta bio-medica : Atenei Parmensis · 2020Article
- Clinical and imaging characteristics of PFO-related stroke with different amounts of right-to-left shunt.Brain and behavior · 2018Article
- Platypnea-Orthodeoxia Syndrome Due to a Functional Patent Foramen Ovale: Aortic Dilatation and Possible Contribution of Obstructive Sleep Apnea.Open respiratory archivesArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Platypnea-orthodeoxia syndrome (POS) is a rare disorder characterized by the emergence of a right-to-left shunt at the intracardiac or intrapulmonary level. The clinical picture is distinguished by shortness of breath that worsens on standing due to an accentuation of oxygen desaturation, and instead improves, at least partly, in the recumbent position. In this article we present a brief review of the pathophysiology of POS, as well as its clinical picture, diagnostic assessment, and preferential therapeutic options. Pathophysiological issues that are still not completely understood or much debated are outlined. The currently accepted pathophysiological concepts are presented and a summary of the main diagnostic and therapeutic tools is provided.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.