ReviewWorld journal of hepatology2016
Dynamics of hepatic and intestinal cholesterol and bile acid pathways: The impact of the animal model of estrogen deficiency and exercise training.
Review in World journal of hepatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 33 citations in OpenAlex.
- Sex and Gender Perspective in Obesity and Gastric Cancer.The world journal of men's health · 2026Review
- U-shaped association between dietary flavonoid and gallstone prevalence with sex-specific effects: Insights from a cross-sectional study.The Journal of international medical research · 2026Article
- Cardiometabolic index as a predictor of gallstone risk: evidence from NHANES 2017-2020.BMC gastroenterology · 2025Article
- Effects of key physiological parameters on cardiovascular disease and osteoporosis risk in perimenopausal and postmenopausal women.Scientific reports · 2025Article
- Body Mass Index mediates the relationship between estimated glucose disposal rate and gallstones.Scientific reports · 2025Article
- Association between ZJU index and gallstones in US adult: a cross-sectional study of NHANES 2017-2020.BMC gastroenterology · 2024Article
- Association of Changes in Relevant Indicators With Cardiovascular Disease and Osteoporosis in Perimenopausal and Postmenopausal Women.Food science & nutrition · 2024Article
- Association between serum iron and gallstones in US adults: a cross-sectional study.BMC nutrition · 2024Article
- Association between triglyceride-glucose index and gallstones: a cross-sectional study.Scientific reports · 2024Article
- Association between weight-adjusted-waist index and gallstones: an analysis of the National Health and Nutrition Examination Survey.BMC gastroenterology · 2024Article
- Cholesterol Transport Dysfunction and Its Involvement in Atherogenesis.International journal of molecular sciences · 2022Review
- Effect of petroleum wastewater treated with gravity separation and magnetite nanoparticles adsorption methods on the blood biochemical response of mrigal fish (Cirrhinus cirrhosus).Environmental science and pollution research international · 2022Article
- Clinical features and outcomes in 38 dogs with cholelithiasis receiving conservative or surgical management.Journal of veterinary internal medicine · 2021Article
- Gender Differences in Obesity-Related Cancers.Current obesity reports · 2021Review
- Effect and related mechanism of Yinchenhao decoction on mice with lithogenic diet-induced cholelithiasis.Experimental and therapeutic medicine · 2021Article
- DSS-induced colitis is associated with adipose tissue dysfunction and disrupted hepatic lipid metabolism leading to hepatosteatosis and dyslipidemia in mice.Scientific reports · 2021Article
- Stress can attenuate hepatic lipid accumulation via elevation of hepatic β-muricholic acid levels in mice with nonalcoholic steatohepatitis.Laboratory investigation; a journal of technical methods and pathology · 2021Article
- Detection technologies and metabolic profiling of bile acids: a comprehensive review.Lipids in health and disease · 2018Review
- Recent advances in understanding and managing cholesterol gallstones.F1000Research · 2018Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plasma cholesterol level is determined by a complex dynamics that involves transport lipoproteins which levels are tightly dependent on how the liver and the intestine regulate cholesterol and biliary acid metabolism. Regulation of cholesterol and biliary acids by the liver and the intestine is in turn coupled to a large array of enzymes and transporters that largely influence the inflow and the outflow of cholesterol and biliary acids through these organs. The activity of the key regulators of cholesterol and biliary acids may be influenced by several external factors such as pharmacological drugs and the nutritional status. In recent years, more information has been gathered about the impact of estrogens on regulation of cholesterol in the body. Exposure to high levels of estrogens has been reported to promote cholesterol gallstone formation and women are twice as likely as men to develop cholesterol gallstones. The impact of estrogen withdrawal, such as experienced by menopausal women, is therefore of importance and more information on how the absence of estrogens influence cholesterol regulation is started to come out, especially through the use of animal models. An interesting alternative to metabolic deterioration due to estrogen deficiency is exercise training. The present review is intended to summarize the present information that links key regulators of cholesterol and biliary acid pathways in liver and intestine to the absence of estrogens in an animal model and to discuss the potential role of exercise training as an alternative.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.