Evidence map›Paper›PMID 27621748›Full record

ArticleKorean journal of hepato-biliary-pancreatic surgery2016

Irreversible electroporation for the treatment of pancreatic neuroendocrine tumors.

Michail Papamichail, Amir Ali, Michail Pizanias, Praveen Peddu, John Karani, Nigel Heaton

Open access · diamondAbstract read
In one paragraph

Article in Korean journal of hepato-biliary-pancreatic surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Non-surgical ablative therapies for inoperable benign insulinoma.Journal of endocrinological investigation · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Michail PapamichailInstitute of Liver Studies, Kings Health Partners at King's College Hospital NHS Trust, London, United Kingdom.
Amir AliInstitute of Liver Studies, Kings Health Partners at King's College Hospital NHS Trust, London, United Kingdom.
Michail PizaniasInstitute of Liver Studies, Kings Health Partners at King's College Hospital NHS Trust, London, United Kingdom.
Praveen PedduInstitute of Liver Studies, Kings Health Partners at King's College Hospital NHS Trust, London, United Kingdom.
John KaraniInstitute of Liver Studies, Kings Health Partners at King's College Hospital NHS Trust, London, United Kingdom.
Nigel HeatonInstitute of Liver Studies, Kings Health Partners at King's College Hospital NHS Trust, London, United Kingdom.
Kings Health Partners · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUNDS/

aimsResection or enucleation is currently the treatment of choice for small pancreatic neuroendocrine tumors (NETs). Irreversible electroporation is a novel ablative method that is used for locally advanced pancreatic adenocarcinoma, but little data exists for its use for pancreatic NETs. We report an early experience of IRE for early pancreatic NETs.

methodsBetween April 2014 and March 2015, 3 patients with small (<2 cm) pancreatic NETs were treated with percutaneous IRE.

resultsThere were no adverse effects during the procedure. Mean hospital stay was 2.6 days. All patients remained disease free on 12-19 months follow up. One patient developed recurrent pancreatitis with pseudocyst formation.

conclusionsIRE for small tumors of the pancreas is practical and may offer advantages over other thermal ablative techniques, since it preserves vital structures such as blood vessels, bile and pancreatic ducts. Further data regarding the long term disease free interval is required to establish efficacy.

Indexed as

Irreversible electroporation (IRE)Non-thermal ablationPancreatic neuroendocrine tumors

Identifiers

PMID27621748
PMCPMC5018952
OpenAlexW2516413505

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.