Evidence map›Paper›PMID 27621636›Full record

ArticleNeuropsychiatric disease and treatment2016

Children who screen positive for autism at 2.5 years and receive early intervention: a prospective naturalistic 2-year outcome study.

Birgitta Spjut Jansson, Carmela Miniscalco, Joakim Westerlund, Anne-Katrin Kantzer, Elisabeth Fernell, Christopher Gillberg

Abstract read
In one paragraph

Article in Neuropsychiatric disease and treatment, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Overall prognosis of preschool autism spectrum disorder diagnoses.The Cochrane database of systematic reviews · 2022
    Pooled it
  2. Intervention Effects on Language in Children With Autism: A Project AIM Meta-Analysis.Journal of speech, language, and hearing research : JSLHR · 2020
    Pooled it
  3. Pooled it
  4. Trial
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  8. Needs of Grandparents of Preschool-Aged Children with ASD in Sweden.Journal of autism and developmental disorders · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Birgitta Spjut JanssonGillberg Neuropsychiatry Centre, Sahlgrenska Academy, Institute of Neuroscience and Physiology, University of Gothenburg; Unit of Child and Adolescent Habilitation; Department of Psychology, University of Gothenburg.
Carmela MiniscalcoGillberg Neuropsychiatry Centre, Sahlgrenska Academy, Institute of Neuroscience and Physiology, University of Gothenburg; Division of Speech and Language Pathology, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg.
Joakim WesterlundGillberg Neuropsychiatry Centre, Sahlgrenska Academy, Institute of Neuroscience and Physiology, University of Gothenburg; Department of Psychology, University of Stockholm, Stockholm.
Anne-Katrin KantzerGillberg Neuropsychiatry Centre, Sahlgrenska Academy, Institute of Neuroscience and Physiology, University of Gothenburg; Department of Child and Adolescent Psychiatry, NU Hospital Organization, Trollhättan, Sweden.
Elisabeth FernellGillberg Neuropsychiatry Centre, Sahlgrenska Academy, Institute of Neuroscience and Physiology, University of Gothenburg.
Christopher GillbergGillberg Neuropsychiatry Centre, Sahlgrenska Academy, Institute of Neuroscience and Physiology, University of Gothenburg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious research has stressed the importance of early identification and intervention for children with autism spectrum disorders.

methodsChildren who had screened positive for autism at the age of 2.5 years in a general population screening and then received a diagnosis of autism spectrum disorder were enrolled in an intervention program provided by Swedish habilitation services. The following interventions were available: a comprehensive intervention based on Applied Behavior Analysis - Intensive Learning (IL) - in two settings, which included home- and preschool-based (IL Regular) and only home-based (IL Modified) and eclectic interventions.

resultsThere was considerable variability in terms of outcome, but intervention group status was not associated with any of the chosen outcome variables.

conclusionThe main finding was that the type of intervention was not critical for outcome of adaptive or global functioning. The variability in outcome demonstrates the need for continuous assessments and evaluation of the child's function and behavior throughout the intervention period.

Indexed as

ABAautism spectrum disordercognitive functionearly interventionfollow-uppreschool children

Identifiers

PMID27621636
PMCPMC5012621

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.