Observational studyWorld journal of gastroenterology2016
Prevalence of colorectal neoplasms in young, average risk individuals: A turning tide between East and West.
Observational study in World journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Early-Age Onset Colorectal Neoplasia in Average-Risk Individuals Undergoing Screening Colonoscopy: A Systematic Review and Meta-Analysis.Gastroenterology · 2021Pooled it
- Demographics of colonic health: Unveiling sex- and age-driven trends in a cross-sectional retrospective analysis of 2523 colonoscopy procedures.The Journal of international medical research · 2025Article
- Colorectal Neoplasia in Vietnamese Patients Under 50 Years of Age: A Cross-Sectional Study.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025Article
- Early Detection and Age-Comparative Analysis of Colorectal Cancer Screening: Insights from the Turkish Population.Current oncology (Toronto, Ont.) · 2025Article
- New considerations for colorectal cancer screening based on the demographic profile of colorectal cancer in a Greek population.Molecular and clinical oncology · 2022Article
- The location of premalignant colorectal polyps under age 50: a further rationale for screening sigmoidoscopy.International journal of colorectal disease · 2020Article
- Alarming endoscopic data in young and older asymptomatic people: Results of an open access, unlimited age colonoscopic screening for colorectal cancer.Molecular and clinical oncology · 2020Article
- A Comparative Study Evaluating the Incidence of Colorectal Neoplasia(s) in Candidates for Bariatric Surgery by Screening Colonoscopy, 40-49 Versus 50-65 Years Old: a Preliminary Study.Obesity surgery · 2019Article
- Higher body mass index is associated with an increased risk of multiplicity in surveillance colonoscopy within 5 years.Scientific reports · 2017Article
- Clinicopathologic features and prognostic factors for patients with colorectal cancer who are 75 years and older.Oncotarget · 2017Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo determine the prevalence of colorectal neoplasia in average risk persons 40-59 years of age in Israel and to compare the results with other populations.
methodsWe reviewed the results of asymptomatic average-risk subjects, aged 40 to 59 years, undergoing their first screening colonoscopy between April 1994 and January 2014. The detection rates of adenoma, advanced adenoma (AA) and colorectal cancer (CRC) were determined in the 40's and 50's age groups by gender. The prevalence of lesions was compared between age groups. After meticulous review of the literature, these results were compared to published studies addressing the prevalence of colorectal neoplasia in similar patient groups, in a variety of geographical locations.
resultsWe included first screening colonoscopy results of 1750 individuals. The prevalence of adenomas, AA and CRC was 8.3%, 1.0% and 0.2% in the 40-49 age group and 13.7%, 2.4% and 0.2% in the 50-59 age group, respectively. Age-dependent differences in adenoma and AA rates were significant only among men (P < 0.005). Literature review disclosed 17 relevant studies. As expected, in both Asian and Western populations, the risks for overall adenoma and advanced adenoma was significantly higher in the 50's age group as compared to the 40's age group in a similar fashion. The result of the current study were similar to previous studies on Western populations. A substantially higher rate of adenoma, was observed in studies conducted among Asian populations in both age groups.
conclusionThe higher rate of colorectal neoplasia in Asian populations requires further investigation and reconsideration as to the starting age of screening in that population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.