Evidence map›Paper›PMID 27621538›Full record

ReviewJournal of toxicologic pathology2016

Nonproliferative and Proliferative Lesions of the Rat and Mouse Skeletal Tissues (Bones, Joints, and Teeth).

Stacey Fossey, John Vahle, Philip Long, Scott Schelling, Heinrich Ernst, Rogely Waite Boyce, Jacquelin Jolette, Brad Bolon, Alison Bendele, Matthias Rinke and 5 more

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of toxicologic pathology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 49 citations in OpenAlex.

  1. British Red Squirrels (Interdisciplinary perspectives on infectious diseases · 2026
    Article
  2. Article
  3. The chordoid gliomaScience signaling · 2025
    Article
  4. Article
  5. Histopathology of spontaneous lesions in FVB/N mice.Journal of toxicologic pathology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Spontaneous chondrosarcoma in Wistar rat: a case report.Journal of toxicologic pathology · 2021
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 4 countries.

Stacey FosseyAbbVie Inc., North Chicago, IL, USA.
John VahleLilly Research Laboratories, Indianapolis, IN, USA.
Philip LongVet Path Services, Inc., Mason, OH, USA.
Scott SchellingPfizer Inc., Andover, MA, USA; Dr. Schelling retired April 2015.
Heinrich ErnstFraunhofer Institute, Hannover, Germany.
Rogely Waite BoyceAmgen Inc., Thousand Oaks, CA, USA.
Jacquelin JoletteCharles River Laboratories, Senneville, Canada.
Brad BolonGEMpath Inc., Longmont, CO, USA.
Alison BendeleBolder BioPath, Inc., Boulder, CO, USA.
Matthias RinkeBayer Pharma AG, Wuppertal, Germany.
Laura HealyLNH Tox Path Consulting, LLC, Kalamazoo, MI, USA.
Wanda HighWB High Preclin Path/Tox Consulting, LLC, Rochester, NY, USA.
Daniel Robert RothAbbVie Inc., North Chicago, IL, USA.
Michael BoyleAmgen Inc., Thousand Oaks, CA, USA.
Joel LeiningerJRL Consulting, LLC, Chapel Hill, NC, USA; Chair of the Skeletal Tissues INHAND Committee.
Amgen (United States) · USAbbVie (United States) · USBayer (Germany) · DEBolder Biotechnology, Inc. · USCanadian Nuclear Laboratories · CAEli Lilly (United States) · USFraunhofer Society · DENewPath Research · USPfizer (United States) · USSwissmedic · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice) Project (www.toxpath.org/inhand.asp) is an initiative of the Societies of Toxicological Pathology from Europe (ESTP), Great Britain (BSTP), Japan (JSTP) and North America (STP) to develop an internationally accepted nomenclature for proliferative and nonproliferative lesions in laboratory animals. The purpose of this publication is to provide a standardized nomenclature for classifying microscopic lesions observed in the skeletal tissues and teeth of laboratory rats and mice, with color photomicrographs illustrating examples of many common lesions. The standardized nomenclature presented in this document is also available on the internet (http://www.goreni.org/). Sources of material were databases from government, academic and industrial laboratories throughout the world.

Indexed as

bonediagnostic criteriadiagnostic pathologyjointnomenclatureskeletal systemtooth

Identifiers

PMID27621538
PMCPMC5013709
OpenAlexW2504317622

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.