ArticleProceedings of the National Academy of Sciences of the United States of America2016
Host-pathogen evolutionary signatures reveal dynamics and future invasions of vampire bat rabies.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
78 citing papers in PubMed, 1 synthesis or guideline pooled it, 141 citations in OpenAlex.
- Influence of Host and Landscape-Associated Factors in the Infection and Transmission of Pathogens: The Case of Directly Transmitted Virus in Mammals.Veterinary medicine and science · 2025Pooled it
- Equine Rabies in Southern Colombia, 2024-2025.Animals : an open access journal from MDPI · 2026Article
- Research Progress in Bat Dietary Analysis: Methods, Applications, and Future Perspectives.Biology · 2026Review
- Virus-Dependent Geographic Structure of Co-Circulating Viruses in a Single Bat Species.Molecular ecology · 2026Article
- Rabies, host population structure, and cross-species transmission to the migratory bat Tadarida brasiliensis in Chile.PLoS neglected tropical diseases · 2026Article
- Superspreading and the evolution of virulence.PLoS computational biology · 2025Article
- Drivers of rabies virus spillover risk from vampire bats to livestock in Colombia.PLoS neglected tropical diseases · 2025Article
- Anticoagulants for the Control of the Common Vampire Bat (Desmodus rotundus).Zoonoses and public health · 2025Review
- Genomic characterization of a dog-mediated rabies outbreak in El Pedregal, Arequipa, Peru.PLoS neglected tropical diseases · 2025Article
- Dynamics of influenza transmission in vampire bats revealed by longitudinal monitoring and a large-scale anthropogenic perturbation.Science advances · 2025Article
- Article
- A time-space Bayesian regression model of rabies cases in the animal population of Kazakhstan (2013-2023).Frontiers in veterinary science · 2025Article
- How fast are viruses spreading in the wild?PLoS biology · 2024Article
- Genomic Characterization of a Dog-Mediated Rabies Outbreak in El Pedregal, Arequipa, Peru.bioRxiv : the preprint server for biology · 2024Article
- Advances in understanding bat infection dynamics across biological scales.Proceedings. Biological sciences · 2024Review
- Genetic structure and Rickettsia infection rates in Ixodes ovatus and Haemaphysalis flava ticks across different altitudes.PloS one · 2024Article
- Dispersion and diversification of Lyssavirus rabies transmitted from haematophagous bats Desmodus rotundus: a phylogeographical study.Virus genes · 2023Article
- Incorporating environmental heterogeneity and observation effort to predict host distribution and viral spillover from a bat reservoir.Proceedings. Biological sciences · 2023Article
- Viral Prevalence and Genomic Xenology in the Coevolution of HzNV-2 (Nudiviridae) with HostInsects · 2023Article
- Effects of culling vampire bats on the spatial spread and spillover of rabies virus.Science advances · 2023Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 5 countries.
Funding
Abstract
Anticipating how epidemics will spread across landscapes requires understanding host dispersal events that are notoriously difficult to measure. Here, we contrast host and virus genetic signatures to resolve the spatiotemporal dynamics underlying geographic expansions of vampire bat rabies virus (VBRV) in Peru. Phylogenetic analysis revealed recent viral spread between populations that, according to extreme geographic structure in maternally inherited host mitochondrial DNA, appeared completely isolated. In contrast, greater population connectivity in biparentally inherited nuclear microsatellites explained the historical limits of invasions, suggesting that dispersing male bats spread VBRV between genetically isolated female populations. Host nuclear DNA further indicated unanticipated gene flow through the Andes mountains connecting the VBRV-free Pacific coast to the VBRV-endemic Amazon rainforest. By combining Bayesian phylogeography with landscape resistance models, we projected invasion routes through northern Peru that were validated by real-time livestock rabies mortality data. The first outbreaks of VBRV on the Pacific coast of South America could occur by June 2020, which would have serious implications for agriculture, wildlife conservation, and human health. Our results show that combining host and pathogen genetic data can identify sex biases in pathogen spatial spread, which may be a widespread but underappreciated phenomenon, and demonstrate that genetic forecasting can aid preparedness for impending viral invasions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.