Evidence map›Paper›PMID 27620989›Full record

ArticleJournal of the American Society of Nephrology : JASN2017

Mitogen-Activated Protein Kinase 14 Promotes AKI.

Alberto Ortiz, Holger Husi, Laura Gonzalez-Lafuente, Lara Valiño-Rivas, Manuel Fresno, Ana Belen Sanz, William Mullen, Amaya Albalat, Sergio Mezzano, Tonia Vlahou and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 51 citations in OpenAlex.

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  16. Target Identification of Active Constituents ofFrontiers in pharmacology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 5 countries.

Alberto OrtizInstituto Investigacion Sanitaria-Fundacion Jimenez Diaz-Universidad Autonoma de Madrid and Fundacion Renal Iñigo Alvarez de Toledo-Instituto Reina Sofia de Investigacion Nefrologica, Madrid, Spain; mdsanchez@fjd.es aortiz@fjd.es.
Holger HusiInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom.
Laura Gonzalez-LafuenteInstituto Investigacion Sanitaria-Fundacion Jimenez Diaz-Universidad Autonoma de Madrid and Fundacion Renal Iñigo Alvarez de Toledo-Instituto Reina Sofia de Investigacion Nefrologica, Madrid, Spain.
Lara Valiño-RivasInstituto Investigacion Sanitaria-Fundacion Jimenez Diaz-Universidad Autonoma de Madrid and Fundacion Renal Iñigo Alvarez de Toledo-Instituto Reina Sofia de Investigacion Nefrologica, Madrid, Spain.
Manuel FresnoCentro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas de la Universidad Autonoma de Madrid, Madrid, Spain.
Ana Belen SanzInstituto Investigacion Sanitaria-Fundacion Jimenez Diaz-Universidad Autonoma de Madrid and Fundacion Renal Iñigo Alvarez de Toledo-Instituto Reina Sofia de Investigacion Nefrologica, Madrid, Spain.
William MullenInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom.
Amaya AlbalatInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom.
Sergio MezzanoUnidad de Nefrología, Instituto de Medicina, Universidad Austral de Chile, Valdivia, Chile; and.
Tonia VlahouBiomedical Research Foundation Academy of Athens, Athens, Greece.
Harald MischakInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom.
Maria Dolores Sanchez-NiñoInstituto Investigacion Sanitaria-Fundacion Jimenez Diaz-Universidad Autonoma de Madrid and Fundacion Renal Iñigo Alvarez de Toledo-Instituto Reina Sofia de Investigacion Nefrologica, Madrid, Spain; mdsanchez@fjd.es aortiz@fjd.es.
Fundación Renal · ESUniversity of Glasgow · GBUniversidad Autónoma de Madrid · ESAcademy of Athens · GRAustral University of Chile · CLConsejo Superior de Investigaciones Científicas · ESMosaiques Diagnostics and Therapeutics (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An improved understanding of pathogenic pathways in AKI may identify novel therapeutic approaches. Previously, we conducted unbiased liquid chromatography-tandem mass spectrometry-based protein expression profiling of the renal proteome in mice with acute folate nephropathy. Here, analysis of the dataset identified enrichment of pathways involving NF

Indexed as

Acute Kidney InjuryAnimalsFemaleMiceMice, Inbred C57BLMitogen-Activated Protein Kinase 14Mitogen-Activated Protein Kinase 14acute kidney injurychemokinekidney tubulerenal failurerenal injury

Identifiers

PMID27620989
PMCPMC5328147
OpenAlexW2519048082

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.