ArticleScientific reports2016
Altered brain ion gradients following compensation for elevated CO2 are linked to behavioural alterations in a coral reef fish.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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28 citing papers in PubMed, 78 citations in OpenAlex.
- Tolerance to future elevated COJournal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026Article
- Ocean acidification induces neuronal hyperexcitation and anxiety-like behaviour in marine medaka via ASIC activation.Fish physiology and biochemistry · 2026Article
- Neurometabolic rewiring in squid (Sepioteuthis lessoniana) optic lobes drives behavioral plasticity and visual integration under environmental acidification.Communications biology · 2026Article
- Neuromolecular responses in disrupted mutualistic cleaning interactions under future environmental conditions.BMC biology · 2023Article
- Brain transcriptome of gobies inhabiting natural COEvolutionary applications · 2023Article
- Rapid evolution fuels transcriptional plasticity to ocean acidification.Global change biology · 2022Article
- Ocean acidification affects the expression of neuroplasticity and neuromodulation markers in seabream.Biology open · 2022Article
- Access to Cleaning Services Alters Fish Physiology Under Parasite Infection and Ocean Acidification.Frontiers in physiology · 2022Article
- The Olfactory Tract: Basis for Future Evolution in Response to Rapidly Changing Ecological Niches.Frontiers in neuroanatomy · 2022Review
- Ocean Acidification Amplifies the Olfactory Response to 2-Phenylethylamine: Altered Cue Reception as a Mechanistic Pathway?Journal of chemical ecology · 2021Article
- Article
- Ocean acidification promotes broad transcriptomic responses in marine metazoans: a literature survey.Frontiers in zoology · 2020Review
- Physiological resilience of pink salmon to naturally occurring ocean acidification.Conservation physiology · 2020Article
- Ocean acidification affects acid-base physiology and behaviour in a model invertebrate, the California sea hare (Royal Society open science · 2019Article
- Article
- Long-term acclimation to near-future ocean acidification has negligible effects on energetic attributes in a juvenile coral reef fish.Oecologia · 2019Article
- A negative correlation between behavioural and physiological performance under ocean acidification and warming.Scientific reports · 2019Article
- Elevated COGlobal change biology · 2019Article
- Neural effects of elevated COConservation physiology · 2019Article
- Effect of elevated COProceedings. Biological sciences · 2018Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neurosensory and behavioural disruptions are some of the most consistently reported responses upon exposure to ocean acidification-relevant CO2 levels, especially in coral reef fishes. The underlying cause of these disruptions is thought to be altered current across the GABAA receptor in neuronal cells due to changes in ion gradients (HCO3(-) and/or Cl(-)) that occur in the body following compensation for elevated ambient CO2. Despite these widely-documented behavioural disruptions, the present study is the first to pair a behavioural assay with measurements of relevant intracellular and extracellular acid-base parameters in a coral reef fish exposed to elevated CO2. Spiny damselfish (Acanthochromis polyacanthus) exposed to 1900 μatm CO2 for 4 days exhibited significantly increased intracellular and extracellular HCO3(-) concentrations and elevated brain pHi compared to control fish, providing evidence of CO2 compensation. As expected, high CO2 exposed damselfish spent significantly more time in a chemical alarm cue (CAC) than control fish, supporting a potential link between behavioural disruption and CO2 compensation. Using HCO3(-) measurements from the damselfish, the reversal potential for GABAA (EGABA) was calculated, illustrating that biophysical properties of the brain during CO2 compensation could change GABAA receptor function and account for the behavioural disturbances noted during exposure to elevated CO2.
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