ArticleHearing research2016
Dopaminergic projections of the subparafascicular thalamic nucleus to the auditory brainstem.
Article in Hearing research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
11 citing papers in PubMed, 35 citations in OpenAlex.
- Brain-wide activity mapping reveals the somatosensory cortex as a sex-specific regulator of hedonic feeding.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Article
- The Potential Role of Dopamine Pathways in the Pathophysiology of Depression: Current Advances and Future Aspects.CNS & neurological disorders drug targets · 2025Review
- Neurotransmitter phenotype and axonal projection patterns of VIP-expressing neurons in the inferior colliculus.Journal of chemical neuroanatomy · 2022Article
- Mapping the vocal circuitry of Alston's singing mouse with pseudorabies virus.The Journal of comparative neurology · 2022Article
- Early auditory responses to speech sounds in Parkinson's disease: preliminary data.Scientific reports · 2022Article
- Dopamine: The Neuromodulator of Long-Term Synaptic Plasticity, Reward and Movement Control.Cells · 2021Review
- Dopamine in Auditory Nuclei and Lemniscal Projections is Poised to Influence Acoustic Integration in the Inferior Colliculus.Frontiers in neural circuits · 2021Article
- Dopamine modulates subcortical responses to surprising sounds.PLoS biology · 2020Article
- Projections of the Diencephalospinal Dopaminergic System to Peripheral Sense Organs in Larval Zebrafish (Frontiers in neuroanatomy · 2018Article
- Dopamine Acts via D2-Like Receptors to Modulate Auditory Responses in the Inferior Colliculus.eNeuroArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Neuromodulators can alter the response properties of sensory neurons, including those in the auditory system. Dopamine, which plays a major role in reward and movement, has been shown to alter neural responses in the auditory brainstem and midbrain. Recently we identified the subparafascicular thalamic nucleus (SPF), part of the A11 dopaminergic cell group, as the source of dopamine to the inferior colliculus (IC). The superior olivary complex (SOC) is also a likely target of dopaminergic projections from the SPF because it receives projections from the SPF and contains fibers and terminals immunoreactive for tyrosine hydroxylase, the rate limiting enzyme in dopamine synthesis. However, it is unknown if the projections from the SPF to SOC are dopaminergic, and if single neurons in the SPF project to both the IC and SOC. Using anterograde tracing combined with fluorescent immunohistochemistry, we found that the SPF sends dopaminergic projections to the superior paraolivary nucleus and the medial nucleus of the trapezoid body, but not the lateral superior olive. We confirmed these projections using a retrograde tracer. By making dual retrograde deposits in the IC and SOC, we found that individual dopaminergic cells innervate both the IC and SOC. These results suggest dopaminergic innervation, likely released in a context dependent manner, occurs at multiple levels of the auditory pathway.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.