Evidence map›Paper›PMID 27620485›Full record

ArticleMedical microbiology and immunology2016

Evaluation of cytotoxicity, immune compatibility and antibacterial activity of biogenic silver nanoparticles.

M Składanowski, P Golinska, K Rudnicka, H Dahm, M Rai

Abstract read
In one paragraph

Article in Medical microbiology and immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Eco-Friendly Synthesis of Silver Nanoparticles UsingInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Therapeutic applications of nanobiotechnology.Journal of nanobiotechnology · 2023
    Review
  19. Article
  20. Silver Nanoparticles Phytofabricated throughAntibiotics (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

M SkładanowskiDepartment of Microbiology, Nicolaus Copernicus University, Lwowska 1, Toruń, Poland.
P GolinskaDepartment of Microbiology, Nicolaus Copernicus University, Lwowska 1, Toruń, Poland. golinska@umk.pl.ORCID http://orcid.org/0000-0001-9154-8191
K RudnickaGastroimmunology Lab., Department of Immunology and Infectious Biology, Institute of Microbiology, Biotechnology and Immunology, Faculty of Biology and Environmental Protection, University of Lódź, Banacha 12/16, Lodz, Poland.
H DahmDepartment of Microbiology, Nicolaus Copernicus University, Lwowska 1, Toruń, Poland.
M RaiNanobiotechnology Lab., Department of Biotechnology, S.G.B. Amravati University, Amravati, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study was focused on assessment of antibacterial activity, cytotoxicity and immune compatibility of biogenic silver nanoparticles (AgNPs) synthesized from Streptomyces sp. NH28 strain. Nanoparticles were biosynthesized and characterized by UV-Vis spectroscopy, transmission electron microscopy, Fourier transform infrared spectroscopy, nanoparticle tracking analysis system and zeta potential. Antibacterial activity was tested against Gram-positive and Gram-negative bacteria; minimal inhibitory concentration was recorded. Cytotoxicity was estimated using L929 mouse fibroblasts via 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide test. Biocompatibility of AgNPs was performed using THP1-XBlue™ cells. Biogenic AgNPs presented high antibacterial activity against all tested bacteria. Minimum inhibitory concentration of AgNPs against bacterial cells was found to be in range of 1.25-10 μg/mL. Silver nanoparticles did not show any harmful interaction to mouse fibroblast cell line, and no activation of nuclear factor kappa-light-chain-enhancer of activated B (NF-κB) cells was observed at concentration below 10 µg/mL. The half-maximal inhibitory concentration (IC

Indexed as

Metal NanoparticlesAnimalsAnti-Bacterial AgentsBacteriaCell LineHumansMiceMicrobial Sensitivity TestsSilverSpectroscopy, Fourier Transform InfraredAnti-Bacterial AgentsSilverActinomycetesAntibacterial activityBiogenic silver nanoparticlesCytotoxicityNF-κB activation

Identifiers

PMID27620485
PMCPMC5093183

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.