ReviewJournal of anatomy2017
The neuroanatomy of autism - a developmental perspective.
Review in Journal of anatomy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
122 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Neurometabolite differences in Autism as assessed with Magnetic Resonance Spectroscopy: A systematic review and meta-analysis.Neuroscience and biobehavioral reviews · 2024Pooled it
- Cognitive Profile in Autism and ADHD: A Meta-Analysis of Performance on the WAIS-IV and WISC-V.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2024Pooled it
- Atypical local brain connectivity in pediatric autism spectrum disorder? A coordinate-based meta-analysis of regional homogeneity studies.European archives of psychiatry and clinical neuroscience · 2024Pooled it
- Androgen levels in autism spectrum disorders: a systematic review and meta-analysis.Frontiers in endocrinology · 2024Pooled it
- Maternal excessive gestational weight gain as a risk factor for autism spectrum disorder in offspring: a systematic review.BMC pregnancy and childbirth · 2020Pooled it
- Vestibular Function in Children with Neurodevelopmental Disorders: A Systematic Review.Journal of autism and developmental disorders · 2019Pooled it
- Individual and Sex Differences in Behavior and Cortical Excitability in the Rat Valproate Model of Autism.Cells · 2026Article
- Transdiagnostic monoamine-based subtyping for attention-deficit/hyperactivity disorder and autism spectrum disorder via unsupervised machine learning.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Signaling Through Girdin Underlies Excessive Cell Morphogenesis Resulting from Depletion of Neurodevelopmental Disorder-Related Neurexin-2.International journal of molecular sciences · 2026Article
- Systems biology and single-cell transcriptome analysis identify potential therapeutic targets and impaired neurogenesis in human cortical development related to autism spectrum disorder.Molecular diversity · 2026Article
- Alteration in hippocampal mitochondria ultrastructure and cholesterol accumulation linked to mitochondrial dysfunction in the valproic acid rat model of autism spectrum disorders.Psychopharmacology · 2026Article
- mMolecular neurobiology · 2026Article
- Convergence and divergence of genes informed by common and rare variants of autism spectrum disorders in tissue-specific pathways and gene networks.Translational psychiatry · 2026Article
- Unraveling the Autism Spectrum Heterogeneity: Insights From ABIDE I Database Using Data/Model-Driven Permutation Testing Approaches.Brain and behavior · 2026Article
- The Neuroimmunology of Autism.Molecular neurobiology · 2025Review
- Autism Spectrum Disorder and Perivascular Spaces: An Integrative Perspective Across the Lifespan.Journal of clinical medicine · 2025Review
- Mini-Basketball for Preschool and School-Aged Children with Autism Spectrum Disorder: A Systematic Review of Randomized Controlled Trials.Healthcare (Basel, Switzerland) · 2025Review
- Sensory and cognitive awareness impairment patterns in children with autism spectrum disorder: a factorial analysis of the underlying constructs.Child and adolescent psychiatry and mental health · 2025Article
- MHNet: Multi-view High-Order Network for Diagnosing Neurodevelopmental Disorders Using Resting-State fMRI.Journal of imaging informatics in medicine · 2025Article
- Neurobiological and Behavioral Heterogeneity in Adolescents with Autism Spectrum Disorder.Brain sciences · 2025Review
62 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Autism Spectrum Disorders (ASDs) are a heterogeneous group of neurodevelopmental disorders that are diagnosed solely on the basis of behaviour. A large body of work has reported neuroanatomical differences between individuals with ASD and neurotypical controls. Despite the huge clinical and genetic heterogeneity that typifies autism, some of these anatomical features appear to be either present in most cases or so dramatically altered in some that their presence is now reasonably well replicated in a number of studies. One such finding is the tendency towards overgrowth of the frontal cortex during the early postnatal period. Although these reports have been focused primarily on the presumed pathological anatomy, they are providing us with important insights into normal brain anatomy and are stimulating new ideas and hypotheses about the normal trajectory of brain development and the function of specific anatomical brain structures. The use of model systems that include genetic model organisms such as the mouse and, more recently, human induced pluripotent stem cell-derived brain organoids to model normal and pathological human cortical development, is proving particularly informative. Here we review some of the neuroanatomical alterations reported in autism, with a particular focus on well-validated findings and recent advances in the field, and ask what these observations can tell us about normal and abnormal brain development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.