ArticleIntensive care medicine2016
Improved survival in critically ill patients: are large RCTs more useful than personalized medicine? No.
Article in Intensive care medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Inhaled antibiotics for treating pneumonia in invasively ventilated patients in intensive care unit: a meta-analysis of randomized clinical trials with trial sequential analysis.Critical care (London, England) · 2024Pooled it
- Effect sizes in ongoing randomized controlled critical care trials.Critical care (London, England) · 2017Pooled it
- Immunomodulation in Pediatric Sepsis: A Narrative Review.Journal of clinical medicine · 2025Review
- Use of extracorporeal blood purification therapies in sepsis: the current paradigm, available evidence, and future perspectives.Critical care (London, England) · 2024Review
- From Research to Practice: Toward the Examination of Combined Interventions for Autism Spectrum Disorders.Brain sciences · 2021Article
- Severity of hypoxemia may explain indeterminate results in pediatric trials of inhaled nitric oxide.Intensive care medicine · 2021Article
- Current use of inotropes in circulatory shock.Annals of intensive care · 2021Article
- Risk-Based Care: Let's Think Outside the Box.Frontiers in medicine · 2021Article
- Opportunities and challenges of clustering, crossing over, and using registry data in the PEPTIC trial.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2020Article
- Exploration of Different Rehabilitation Routes for Sepsis Survivors with Monitoring of Health Status and Quality of Life: RehaSep Trial Protocol.Advances in therapy · 2019Observational
- Patient selection in sepsis: precision medicine using phenotypes and its implications for future clinical trial design.Journal of thoracic disease · 2019Article
- Outcomes of critical illness: what is meaningful?Current opinion in critical care · 2018Review
- Next-generation, personalised, model-based critical care medicine: a state-of-the art review of in silico virtual patient models, methods, and cohorts, and how to validation them.Biomedical engineering online · 2018Review
- The coming era of precision medicine for intensive care.Critical care (London, England) · 2017Review
- Personalised fluid resuscitation in the ICU: still a fluid concept?Critical care (London, England) · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
27620286What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.