Evidence map›Paper›PMID 27620064›Full record

Trial reportAnnals of biomedical engineering2017

Dependence of Muscle Moment Arms on In Vivo Three-Dimensional Kinematics of the Knee.

Alessandro Navacchia, Vasiliki Kefala, Kevin B Shelburne

Abstract readClinical Trial
In one paragraph

Trial report in Annals of biomedical engineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  14. Loading and kinematic profiles for patellofemoral durability testing.Journal of the mechanical behavior of biomedical materials · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alessandro NavacchiaCenter for Orthopaedic Biomechanics, The University of Denver, Denver, CO, USA. alessandro.navacchia@du.edu.
Vasiliki KefalaCenter for Orthopaedic Biomechanics, The University of Denver, Denver, CO, USA.
Kevin B ShelburneCenter for Orthopaedic Biomechanics, The University of Denver, Denver, CO, USA.

Funding

A Multi-Scale Finite Element Musculoskeletal Modeling Framework Applied to CurrenR01EB015497 · NIBIB · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI SHELBURNE, KEVIN B · 2012 to 2015
$1.1M
NIBIB NIH HHS R01 EB015497
6 · The paper itself

Abstract

Quantification of muscle moment arms is important for clinical evaluation of muscle pathology and treatment, and for estimating muscle and joint forces in musculoskeletal models. Moment arms estimated with musculoskeletal models often assume a default motion of the knee derived from measurements of passive cadaveric flexion. However, knee kinematics are unique to each person and activity. The objective of this study was to estimate moment arms of the knee muscles with in vivo subject- and activity-specific kinematics from seven healthy subjects performing seated knee extension and single-leg lunge to show changes between subjects and activities. 3D knee motion was measured with a high-speed stereo-radiography system. Moment arms of ten muscles were estimated in OpenSim by replacing the default knee motion with in vivo measurements. Estimated inter-subject moment arm variability was similar to previously reported in vitro measurements. RMS deviations up to 9.0 mm (35.2% of peak value) were observed between moment arms estimated with subject-specific knee extension and passive cadaveric motion. The degrees of freedom that most impacted inter-activity differences were superior/inferior and anterior/posterior translations. Musculoskeletal simulations used to estimate in vivo muscle forces and joint loads may provide significantly different results when subject- and activity-specific kinematics are implemented.

Indexed as

Models, BiologicalAgedBiomechanical PhenomenaFemaleHumansKneeMaleMiddle AgedMovementMuscle, SkeletalFluoroscopyMuscle forceMusculoskeletal modelingSubject-specific

Identifiers

PMID27620064
PMCPMC5411230

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.