Evidence map›Paper›PMID 27619809›Full record

ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2017

Albumin-Bilirubin Score: Predicting Short-Term Outcomes Including Bile Leak and Post-hepatectomy Liver Failure Following Hepatic Resection.

Nikolaos Andreatos, Neda Amini, Faiz Gani, Georgios A Margonis, Kazunari Sasaki, Vanessa M Thompson, David J Bentrem, Bruce L Hall, Henry A Pitt, Ana Wilson and 1 more

Abstract read
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Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it, 101 citations in OpenAlex.

  1. Pooled it
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  11. Postoperative Liver Failure: Definitions, Risk factors, Prediction Models and Prevention Strategies.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Nikolaos AndreatosDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Neda AminiDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Faiz GaniDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Georgios A MargonisDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Kazunari SasakiDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Vanessa M ThompsonNational Surgical Quality Improvement Program, American College of Surgeons, Chicago, IL, USA.
David J BentremDepartment of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Bruce L HallDepartment of Surgery, Washington University School of Medicine at St. Louis, St. Louis, MO, USA.
Henry A PittDepartment of Surgery, Temple University Health System, Philadelphia, PA, USA.
Ana WilsonDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Timothy M PawlikDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA. tim.pawlik@osumc.edu.
Johns Hopkins Medicine · USJohns Hopkins University · USAmerican College of Surgeons · USNorthwestern University · USTemple University Health System · USThe Ohio State University Wexner Medical Center · USWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPost-operative bile leak (BL) and post hepatectomy liver failure (PHLF) are the major potential sources of morbidity among patients undergoing liver resection. We sought to define the incidence of BL and PHLF among a large cohort of patients, as well as examine the prognostic impact of model for end-stage liver disease (MELD) and albumin-bilirubin (ALBI) scores to predict these short-term outcomes. MATERIALS AND

methodsPatients who underwent a hepatectomy between January 1, 2014 and December 31, 2014 were identified using the National Surgical Quality Improvement Program (NSQIP) liver-targeted database. Risk factors for BL and PHLF were identified using multivariable logistic regression.

resultsAmong the 3064 patients identified, median age was 60 years (IQR 50-68). Most patients underwent surgery (78.9 %) for malignant lesions. Post-operatively, 250 (8.5 %) patients experienced a BL while PHLF occurred in 149 cases (4.9 %). Both MELD (MELD <10 4.9 %; MELD ≥10, 10 %; P = 0.001) and ALBI (grade 1, 4.0 %; grade 2, 7.2 %; grade 3, 10.0 %; P = 0.001) were associated with PHLF occurrence, while only ALBI predicted PHLF severity (P = 0.008). Moreover, ALBI was associated with BL (grade 1, 7.1 %; grade 2, 11.5 %; grade 3, 14.0 %; P < 0.001), whereas MELD was not (MELD <10, 8.4 %; MELD ≥10, 11.2 %; P = 0.13). On multivariable analysis, ALBI grade 2/3 was associated with PHLF (OR 1.57, 95 % CI 1.08-2.27; P = 0.02), PHLF severity (OR 3.06, 95 % CI 1.50-6.23; P = 0.003), and the development of a BL (OR 1.35, 95 % CI 1.02-1.80; P = 0.04).

conclusionThe ALBI score was associated with short-term post-operative outcomes following hepatic resection and represents a useful pre-operative risk-assessment tool to identify patients at risk for adverse post-operative outcomes.

Indexed as

BileAgedAnastomotic LeakBilirubinFemaleHepatectomyHumansLiver FailureMaleMiddle AgedPostoperative PeriodPredictive Value of TestsPrognosisRisk AssessmentRisk FactorsSerum AlbuminBilirubinSerum AlbuminAlbuminBile leakBilirubinLiver failureMELDOutcomes

Identifiers

PMID27619809
OpenAlexW2518748823

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.